Search for dissertations about: "protein structure modeling"

Showing result 1 - 5 of 85 swedish dissertations containing the words protein structure modeling.

  2. 1. Protein Structure Prediction : Model Building and Quality Assessment

    Author : Björn Wallner; Arne Elofsson; Michael Levitt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; proteinstrukturförutsägelse; Bioinformatics; Bioinformatik;

    Abstract : Proteins play a crucial roll in all biological processes. The wide range of protein functions is made possible through the many different conformations that the protein chain can adopt. The structure of a protein is extremely important for its function, but to determine the structure of protein experimentally is both difficult and time consuming. READ MORE

  4. 2. Ensemble methods for protein structure prediction

    Author : Marcin J. Skwark; Arne Elofsson; Michael Tress; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; model quality assessment; contact prediction; homology modeling; ab-initio prediction; consensus prediction; structural bioinformatics; bioinformatics; protein structure; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Abstract : Proteins play an essential role in virtually all of life's processes. Their function is tightly coupled to the three-dimensional structure they adopt.Solving protein structures experimentally is a complicated, time- and resource-consuming endeavor. READ MORE

  5. 3. Physical Modeling of Protein Folding

    Author : Stefan Wallin; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; relativity; quantum mechanics; classical mechanics; three-helix bundle; similarity measure; Mathematical and general theoretical physics; protein dynamics; protein folding; two-state; Matematisk och allmän teoretisk fysik; thermodynamics; statistical physics; gravitation; klassisk mekanik; kvantmekanik; relativitet; statistisk fysik; termodynamik; Fysicumarkivet A:2003:Wallin;

    Abstract : Sequence-based models for protein folding are developed and tested on peptides with both alpha- and beta-structure, and on small three-helix-bundle proteins. The interaction potentials of the models are minimalistic and based mainly on hydrogen bonding and effective hydrophobicity forces. READ MORE

  6. 4. Prediction, modeling, and refinement of protein structure

    Author : Per Larsson; Arne Elofsson; Erik Lindahl; Barry Honig; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein structure prediction; Multiple alignments; Quality assessment; Molecular dynamics; Implicit solvent; Refinement; Bioinformatics; Bioinformatik; Bioinformatics; Bioinformatik; Statistical mechanics; Statistisk mekanik; Biochemistry; biokemi;

    Abstract : Accurate predictions of protein structure are important for understanding many processes in cells. The interactions that govern protein folding and structure are complex, and still far from completely understood. However, progress is being made in many areas. Here, efforts to improve the overall quality of protein structure models are described. READ MORE

  7. 5. Structural modeling of membrane transporter proteins

    Author : Jonas Almqvist; Sven Hovmöller; David van der Spoel; Stockholms universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; membrane protein structure; membrane protein crystallography; membrane protein structure modelling; Structural biochemistry; Strukturbiokemi; strukturkemi; Structural Chemistry;

    Abstract : A fundamental process of all living organisms - the transport of molecules across cellular membranes through membrane transport proteins - is investigated.After a brief review of general properties of biological membranes follows a recollection of the major methods of membrane transport that Nature utilizes (Chapter 1). READ MORE