Search for dissertations about: "protein structure."

Showing result 21 - 25 of 1620 swedish dissertations containing the words protein structure..

  2. 21. Protein folding without loops and charges

    Author : Martin Kurnik; Mikael Oliveberg; Kevin W. Plaxco; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; folding cooperativity; protein aggregation; protein charges; protein engineering; Biochemistry; biokemi;

    Abstract : Going down the folding funnel, proteins may sample a wide variety of conformations, some being outright detrimental to the organism. Yet, the vast majority of polypeptide molecules avoid such pitfalls. Not only do they reach the native minimum of the energy landscape; they do so via blazingly fast, biased, routes. READ MORE

  4. 22. Transmembrane Proteins and Protein Structure Prediction : What we can learn from Computational Methods

    Author : John Lamb; Arne Elofsson; Paolo Marcatili; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; contact prediction; transmembrane protein; topology prediction; machine learning; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : A protein’s 3D-structure is essential to understand how proteins function and interact and how biochemical processes proceed in organic life. Despite the advancement in experimental methods, it remains expensive and time-consuming to determine protein structure experimentally. READ MORE

  5. 23. Unlocking protein sequences : Advances in protein structure and ligand-binding site prediction

    Author : Aditi Shenoy; Arne Elofsson; Geoffrey J Barton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : The protein sequence determines how it will fold into its unique three-dimensional structure. Once folded, proteins perform their functions by interacting with other proteins or molecules called ligands within the cell. Experimental determination of protein structure and function is tedious. READ MORE

  6. 24. An evolutionary basis for protein design and structure prediction

    Author : Christoffer Norn; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Biophysics; Protein design; Protein structure prediction;

    Abstract : The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design new protein functions. READ MORE

  7. 25. Learning Protein Evolution and Structure

    Author : Patrick Bryant; Arne Elofsson; Paul Bates; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein structure prediction; Evolution; AI; AlphaFold; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : By analysing the structure of a protein it is possible to draw conclusions about its function. Obtaining the structure of a protein experimentally is however a time consuming and expensive process. By using evolution it is possible to infer the structure of a protein. READ MORE