Search for dissertations about: "protein tyrosine phosphatase"

Showing result 1 - 5 of 47 swedish dissertations containing the words protein tyrosine phosphatase.

  1. 1. Protein tyrosine phosphatase L1 and interacting proteins

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jan Saras; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  2. 2. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Camilla Persson; Arne Östman; Niels Peter Moller; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; protein tyrosine phosphatase; tyrosine kinase; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). READ MORE

  3. 3. The receptor tyrosine kinase Met and the protein tyrosine phosphatase PTPN2 in breast cancer

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Cynthia Veenstra; Olle Stål; Gizeh Perez-Tenorio; Pietras Kristian; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Breast cancer is the most common form of cancer in women worldwide and the second leading cause of cancer death. It is a heterogeneous disease and is subdivided into different subtypes, all with different treatment responses and survival outcomes. READ MORE

  4. 4. Computer Simulation of Protein Tyrosine Phosphatase Reaction Mechanisms and Dihydrofolate Reductase Inhibition

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Karin Kolmodin; Ernst-Walter Knapp; [2001]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Protein tyrosine phosphatases catalyse the hydrolysis of phosphotyrosine residues in proteins, which is an important reaction in the cell signalling system. The three dimensional structure of such a protein tyrosine phosphatase has been used in a computational study of the reaction mechanism at the atomic level. READ MORE

  5. 5. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susann Karlsson; Carina Hellberg; Carl-Henrik Heldin; Bengt Hallberg; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; TC-PTP; receptor trafficking; PK-M2; MEDICINE Morphology; cell biology; pathology Cell biology Medical cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Medicinsk cellbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. READ MORE