Search for dissertations about: "proteinsyntes"

Showing result 1 - 5 of 20 swedish dissertations containing the word proteinsyntes.

  2. 1. Macrolide Antibiotics in Bacterial Protein Synthesis

    Author : Martin Lovmar; Måns Ehrenberg; Tanel Tenson; Peter B. Moore; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein synthesis; macrolides; resistance; initiation of translation; non-competitive inhibitors; kinetics; translation accuracy; proof-reading; Biokemi; Biochemistry; Biokemi;

    Abstract : Macrolides are a large group of clinically relevant antibiotics that inhibit protein synthesis by binding to the large ribosomal subunit in the peptide exit tunnel, close to the peptidyl transferase center (PTC). We have shown that the peptide length of the resulting peptidyl-tRNA drop-off products is proportional to the distance between the PTC and the respective macrolide in the tunnel. READ MORE

  4. 2. Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia

    Author : Jenny Westin; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein synthesis; Nukleinsyror; proteinsyntes; neurofysiologi; Nucleic acids; Neurologi; neuropsykologi; L-DOPA; Dopamine; Neurology; neuropsychology; neurophysiology; Parkinson s disease;

    Abstract : Parkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. READ MORE

  5. 3. The Biological Role of the Female Sex Hormone Estrogen in the Periodontium

    Author : Daniel Jönsson; Malmö högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontal ligament cells; Estrogen receptor;

    Abstract : Introduktion: Flera studier har påpekat att det kan finnas ett samband mellan förändringar i nivån av kvinnligt könshormon och förvärrad tandlossning. Hur östrogen påverkar tandfästet är inte kartlagt. Det finns två östrogenreceptorer (ER), ERα och ERβ och betydelsen av de båda receptorerna är inte kartlagda. READ MORE

  6. 4. On the role of the fusion protein DEK-NUP214 in leukemogenesis

    Author : Malin Ageberg; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mRNA translation; Medicin människa och djur ; fusion gene; Medicine human and vertebrates ; leukemia;

    Abstract : The t(6;9) translocation is found in a subset of patients with acute myeloid leukemia (AML) and is associated with a poor prognosis. The translocation results in the formation of the DEK-NUP214 fusion protein containing almost the entire nuclear protein DEK and two thirds of the nucleoporin NUP214. READ MORE

  7. 5. Signalling in plant mitochondria. Redox regulation of gene expression & characterisation of a pea nucleoside diphosphate kinase

    Author : Martha L Escobar Galvis; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondrial gene expression; redox; respiratory complex II; NDPK; protein interactions; heat-stress; Växtbiokemi; Plant biochemistry;

    Abstract : This work contributes to our understanding of mitochondrial responses to changing environmental conditions in plants. The first part of this thesis is focused in the study of redox regulation of mitochondrial gene expression. By using inhibitors, the redox state of the components of the mitochondrial respiratory chain was selectively affected. READ MORE