Search for dissertations about: "proteogenomics"
Found 5 swedish dissertations containing the word proteogenomics.
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1. Proteogenomic profiling of metastatic melanoma. From protein expression to patient stratification
Abstract : .... READ MORE
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2. Multi-omics analysis of relapsed acute myeloid leukemia
Abstract : The prognosis for patients suffering from acute myeloid leukemia (AML) remains unsatisfactory and survival is often measured in months. Although the majority of patients achieve complete remission after aggressive treatment, most of them relapse within a few years. READ MORE
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3. Cancer proteogenomics : connecting genotype to molecular phenotype
Abstract : The central dogma of molecular biology describes the one-way road from DNA to RNA and finally to protein. Yet, how this flow of information encoded in DNA as genes (genotype) is regulated in order to produce the observable traits of an individual (phenotype) remains unanswered. Recent advances in high-throughput data, i.e. READ MORE
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4. Mass spectrometry based proteomics : data analysis and applications
Abstract : Mass spectrometry (MS) based proteomics has become a widely used high throughput method to investigate protein expression and functional regulation. From being able to study only dozens of proteins, state-of-art MS proteomic techniques are now able to identify and quantify ten thousand proteins. READ MORE
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5. At the intersection of proteomics and pathology : application of mass spectrometry-based protein quantification to histopathology and antibody validation
Abstract : The paradigm of Precision Medicine relies on the molecular stratification of patients to select “the right patient for the right drug”. The genomic approach has tried to answer this question, but large genomic studies have raised more questions than given answers. READ MORE