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Showing result 1 - 5 of 43 swedish dissertations matching the above criteria.

  1. 1. Clinical application of intensity and energy modulated radiotherapy with photon and electron beams

    Author : Xiangkui Mu; Björn Zackrisson; Mikael Karlsson; Thomas Björk-Eriksson; Erik Blomquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; IMXT; IMET; IMPT; proton beams; electron beams; treatment planning; cancer induction; side-effects; fraction time; intensity modulated radiotherapy; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Abstract : In modern, advanced radiotherapy (e.g. intensity modulated photon radiotherapy, IMXT) the delivery time for each fraction becomes prolonged to 10-20 minutes compared with the conventional, commonly 2-5 minutes. The biological effect of this prolongation is not fully known. READ MORE

  2. 2. Beam Modelling for Treatment Planning of Scanned Proton Beams

    Author : Peter Kimstrand; Bengt Glimelius; Erik Traneus; Nina Tilly; Anders Ahnesjö; Thomas Bortfeld; Uppsala universitet; []
    Keywords : Radiation sciences; proton therapy; treatment planning; beam modelling; dose calculation; Monte Carlo; Strålningsvetenskap;

    Abstract : Scanned proton beams offer the possibility to take full advantage of the dose deposition properties of proton beams, i.e. the limited range and sharp peak at the end of the range, the Bragg peak. READ MORE

  3. 3. Studies of clinical proton dosimetry using Monte Carlo simulation and experimental techniques

    Author : Joakim Medin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proton dosimetry; Proton stopping power; Monte Carlo; Proton stopping-power ratios; Ionization chamber calibration; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : The present work aims at improving clinical proton dosimetry based on ionization chambers, and to bring its state of development closer to the corresponding status of conventional photon and electron dosimetry. In order to accomplish this, both theoretical and experimental methods have been used. READ MORE

  4. 4. Micro/nanometric Scale Study of Energy Deposition and its Impact on the Biological Response for Ionizing Radiation : Brachytherapy radionuclides, proton and carbon ion beams

    Author : Fernanda Villegas Navarro; Anders Ahnesjö; Carmen Villagrasa; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionizing radiation; Monte Carlo track structure code; Microdosimetric spread; Energy deposition clustering; RBE; Medicinsk radiofysik; Medical Radiophysics;

    Abstract : Research in radiotherapy for cancer treatment focuses on finding methods that can improve the compromise between tumour cell inactivation versus damage to the surrounding healthy tissue. As new radiation modalities such as proton therapy become accessible for everyday clinical practice, a better understanding of the variation in biological response of the tumour and healthy tissues would improve treatment planning to achieve optimal outcome. READ MORE

  5. 5. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

    Author : Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. READ MORE