Search for dissertations about: "protoporphyrin IX PpIX"

Showing result 1 - 5 of 10 swedish dissertations containing the words protoporphyrin IX PpIX.

  2. 1. Photodynamic therapy and laser-based diagnostic studies of malignant tumours

    Author : Ingrid Wang; Medicinskt lasercentrum; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protoporphyrin IX PpIX ; delta -aminolevulinic acid ALA ; photosensitizer; basal cell carcinoma BCC ; Photodynamic therapy PDT ; laser-induced fluorescence LIF ; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Two non-thermal regimens of light interaction with biological tissue, that are in a natural way connected, are discussed in the present thesis. These are photodynamic therapy (PDT) for the treatment of malignant tumours and laser-induced fluorescence (LIF) for tissue characterization. READ MORE

  4. 2. On the use of light for the characterization and treatment of malignant tumours

    Author : Claes af Klinteberg; Atomfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Diffusion equation; Aminolevulinic acid; Protoporphyrin IX; Photodynamic therapy; Fluorescence spectroscopy; Fluorescence imaging; Laser-Doppler perfusion imaging; Atom- och molekylärfysik; Atomic and molecular physics; Multiple scattering; Tissue optics; Tissue optical properties; Fysicumarkivet A:1999:Klinteberg;

    Abstract : Some aspects on the use of light for tissue characterization and treatment of malignant tumours are discussed within this thesis. The work presented aims at improving optical techniques for tissue characterization, especially to detect malignant and pre-malignant lesions. READ MORE

  5. 3. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

    Author : Vladimir Kirejev; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

    Abstract : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. READ MORE

  6. 4. Photodynamic therapy in the head and neck

    Author : Mathias von Beckerath; Claes Möller; Göran Laurell; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Photo Dynamic Therapy; Cancer; Skin; Larynx; 5-ALA; UVradiation; sarcoma; squamous cell carcinoma; porfimer sodium; temoporfin; voice; Kirurgi; Surgery;

    Abstract : Photodynamic therapy, PDT, is a method to diagnose and treat cancer. In PDT a sensitizer is administered to the patient and this sensitizer is accumulated in tumors. If the sensitizer-containing tumor is subjected to a laser of a specific wavelength the tumor is fluorescing allowing diagnostics. READ MORE

  7. 5. A theoretical study of 5-Aminolevulinic acid and its esters : properties and lipid permeability

    Author : Edvin Erdtman; Leif Eriksson; Fahmi Himo; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Abstract : 5-aminolevulinic acid (5ALA) is a widely used prodrug in Photodynamic therapy (PDT). The target molecule in 5ALA-PDT is Protoporphyrin IX (PpIX), which is synthesized endogenously via the heme pathway in the cell. READ MORE