Search for dissertations about: "proximity extension assay"
Showing result 16 - 20 of 37 swedish dissertations containing the words proximity extension assay.
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16. Antibody-based Cancer Immunotherapy : Personalization, response prediction and safety considerations
Abstract : Antibody-based therapeutics have remarkably improved the field of immuno-oncology. Multiple monoclonal antibodies (mAbs) are approved for clinical use, and numerous antibodies are under clinical development. The scope of this thesis is to study the personalization of antibody-based immunotherapeutics and tools to predict their efficacy and safety. READ MORE
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17. Targeted multiplex proteomics for risk stratification in patients with cardiovascular disease
Abstract : Risk stratification is valuable in patients with cardiovascular disease (CVD). Proteins involved in different pathophysiological processes in atherosclerosis have shown prognostic capacity. A new technology, Proximity Extension Assay (PEA), enables the simultaneous analysis of numerous plasma proteins from a minimal amount of plasma. READ MORE
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18. Exploring Links between Melatonin, Inflammation and Depression
Abstract : Major depressive disorder (MDD) is one of the leading global causes of disease burden. Worse yet, about one third of the patients with MDD do not experience a remission with current treatments. READ MORE
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19. Immunologic Markers in the Tumor Microenvironment of Classical Hodgkin Lymphoma
Abstract : In classical Hodgkin lymphoma (cHL), cytokine regulation and cellular composition of the tumor microenvironment (TME) is crucial for tumor cell survival. In paper I, we examined the presence of CD138+ plasma cells and IgG4+ plasma cells in diagnostic cHL biopsies with immunohistochemistry (IHC). READ MORE
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20. Influence of bone-associated and cardiovascular biomarkers on vascular events and mortality in relation to renal dysfunction
Abstract : Biomarkers can help physicians identify subjects with an increased cardiovascular risk. Apart from the clinical factors, some biomarkers have been recognized as important predictors and risk factors for cardiovascular disease in renal disease. READ MORE