Search for dissertations about: "pteridine"

Found 4 swedish dissertations containing the word pteridine.

  2. 1. Pteridine dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1

    Author : Olov Ekwall; Uppsala universitet; []
    Keywords : Medical sciences; APS I; alopecia; autoantigen; cDNA; malabsorption; phenylalanine hydroxylase; pteridine; tryptophan hydroxylase; tyrosine hydroxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Autoimmune polyendocrine syndrome type I (APS) is a monogenous, recessively inherited disease characterised by endocrine and non-endocrine autoimmune manifestations. One fifth of APS I patients suffer from periodic intestinal dysfunction with varying degrees of malabsorbtion, steatorrhea and constipation. READ MORE

  4. 2. Aspects of direct method procedures for solving crystal structures : applications to isoalloxazine and pteridine derivatives and some comments on the structural chemisty of flavin compounds

    Author : Rolf Norrestam; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  5. 3. Understanding evolutionary novelty through female-limited polymorphisms

    Author : Kalle Tunström; Christopher W. Wheat; Rhonda R. Snook; Patrícia Beldade; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; populationsgenetik; Population Genetics;

    Abstract : Understanding how novel traits evolve is a central question in evolutionary biology. However, unraveling the complex genetic and developmental mechanisms underlying trait innovation can be challenging, especially when the trait evolved a long time ago. READ MORE

  6. 4. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification

    Author : Elisabet Vikeved; UCM Alsmark; Christian Sköld; David Horn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leishmaniasis; Drug discovery; Lateral gene transfer; Comparative genomics; Virtual screening; Target fishing; Marine natural products;

    Abstract : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. READ MORE