Search for dissertations about: "pulmonary blood flow"

Showing result 16 - 20 of 85 swedish dissertations containing the words pulmonary blood flow.

2. 16. Inflammatory mechansims in pulmonary sarcoidosis

   Author : Mary Berlin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adhesion molecules; alveolitis; bronchoalveolar lavage; bronchial hyperreactivity; extracellular matrix molecules; extrinsic allergic alveolitis; fibrosis; HLA-DR; sarcoidosis; TCR;

   Abstract : Pulmonary sarcoidosis is an inflammatory disorder of unknown aetiology, characterised by an accumulation of CD4+ T-cells in the alveolar compartment and by granuloma formation and varying degrees of interstitial fibrosis. The initial clinical presentation may either be acute with fever, malaise, arthritis and/or erythema nodosum or insidious with cough, dyspnea, tiredness, and loss of weight. READ MORE

4. 17. Systemic sclerosis : vascular, pulmonary and immunological aspects

   Author : Grethe Neumann Andersen; Solbritt Rantapää Dahlqvist; Lucia Mincheva-Nilsson; Sören Jacobsen; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; Rheumatology; Reumatologi;

   Abstract : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. READ MORE

5. 18. Evaluation and development of a capnodynamic method for estimation of pulmonary blood flow in a porcine model

   Author : Caroline Hällsjö Sander; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cardiac output;

   Abstract : Effective pulmonary blood flow (EPBF) i.e. cardiac output (CO) minus shunt flow could be estimated by a capnodynamic equation. Via introduction of short pauses in the ventilatory pattern the required alterations of carbon dioxide are induced. READ MORE

6. 19. Benefits of Spontaneous Breathing : Compared with Mechanical Ventilation

   Author : László Vimláti; Michael Lichtwarck-Aschoff; Anders Larsson; Lars Wiklund; Carl-Johan Wickerts; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spontaneous breathing; mechanical ventilation; pulmonary shunt; oxygenation; hypoxic pulmonary vasoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Abstract : When spontaneous breathing (SB) is allowed during mechanical ventilation (MV), atelectatic lung areas are recruited and oxygenation improves thereby. Whether unsupported SB at its natural pattern (without PEEP and at low pressure/small tidal volume) equally recruits and improves oxygenation, and if so by which mechanism, has not been studied. READ MORE

7. 20. Capnodynamic determination of effective pulmonary blood flow and end expiratory lung volume : studies in children and paediatric animal models

   Author : Jacob Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cardiac output children;

   Abstract : Dynamic capnography is a haemodynamic and respiratory monitoring technique enabling continuous cardiac output (Effective Pulmonary Blood Flow, COEPBF) and end expiratory lung volume (Effective Lung Volume, ELV) assessment in mechanically ventilated subjects. The method utilizes variations in exhaled CO2, implemented via periods of deliberate changes in the respiratory pattern. READ MORE