Search for dissertations about: "pulmonary emphysema"

Showing result 21 - 25 of 26 swedish dissertations containing the words pulmonary emphysema.

  2. 21. Alpha-1-antitrypsin deficiency (PiZ): Clinical studies with special regard to hepatic and vasculitic disorders

    Author : Abdul-Nasser Elzouki; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; systemic vasculitis; small-vessel vasculitis; serpins; genetic hemochromatosis; chronic hepatitis C; chronic liver disease; Alpha-1-antitrypsin deficiency; alpha-1-antichymotrypsin deficiency; Gastroenterologi; Urology; nephrology; Urologi; nefrologi;

    Abstract : Homozygous alpha-1-antitrypsin (AAT)deficiency (PiZZ) is known to predispose to emphysema and chronic liver disease (CLD). The overall aim of the studies upon which this thesis is based was to investigate extra-pulmonary disease manifestations of AAT deficiency with special reference to hepatic and vasculitic disorders. READ MORE

  4. 22. Secretory Leukocyte Protease Inhibitor (SLPI) in the gastrointestinal tract in man

    Author : Max Nyström; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; elastase inhibitors; human leukocyt proteases; Plasma protease inhibitors; NGAL; Ulcerative colitis; Antileukoprotease; IBD; traumatologi; ortopedi; traumatology; orthopaedics; Immunology; serology; transplantation; Immunologi; serologi; Kirurgi;

    Abstract : Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. READ MORE

  5. 23. Structure of the distal lung studied with inhaled nanoparticles

    Author : Madeleine Petersson Sjögren; Metalund; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Techniques able to detect impairments in the distal human lung are lacking. Since inhaled nanoparticles are predominantly deposited in the acini, their deposition can be used to derive structural properties of the region. Intheory, structural enlargements in the distal lung imply that less inhaled nanoparticles deposit there. READ MORE

  6. 24. T cells and smoke-induced airway inflammation

    Author : Mikael Mikko; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic obstructive pulmonary disease (COPD) is an inflammatory disease primarily caused by longterm cigarette smoking. The disease is characterized by both tissue remodelling and an accumulation of inflammatory cells including macrophages, neutrophils and T cells, in the lung. READ MORE

  7. 25. Characterization of Pleiotropic Activities of alpha1-Antitrypsin

    Author : Caroline Sandström; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; alpha1-Antitrypsin deficiency; alpha1-Antitrypsin;

    Abstract : Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease characterized by chronic inflammatory response in the airways and lung parenchyma that involves the influx of inflammatory, structural cells and mediators. The inflammatory process resulting in lung tissue destruction, emphysema, includes the excess of uninhibited proteases released from inflammatory cells. READ MORE