Search for dissertations about: "purine metabolism"

Showing result 1 - 5 of 15 swedish dissertations containing the words purine metabolism.

  2. 1. Experimental and clinical studies on human purine metabolism

    Author : Frank Niklasson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei

    Author : Munender Vodnala; Anders Hofer; Arne Holmgren; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Trypanosoma brucei; adenosine kinase; thymidine kinase; methylthioadenosine phosphorylase; mouser ribonucleotide reductase; E. coli ribonucleotide reductase; RNR; Ara-A; F-Ara-A; dNTP; NTP; doexynucleotide metabolism; nucleosides; nucleoside kinases; allosteric regulation; biologisk kemi; biological chemistry;

    Abstract : Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs.T. READ MORE

  5. 3. Myocardial energy metabolism in ischemic preconditioning, role of adenosine catabolism

    Author : Mohammad Kavianipour; Umeå universitet; []
    Keywords : Ischemic preconditioning; adenosine; purine nucleoside phosphorylase; microdialysis; pig; Medicine; medicin;

    Abstract : Brief episodes of ischemia and reperfusion render the myocardium more resistant to necrosis from a subsequent, otherwise lethal ischemic insult. This phenomenon is called ischemic preconditioning(IP). READ MORE

  6. 4. The use of allopurinol and biodynamic modeling in the quantitative assessment of purine metabolism in man

    Author : Geert van Waeg; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  7. 5. Pharmacological studies on uptake, metabolism, and resistance to anti-cancer drugs : insights into the treatment of leukemia

    Author : Hazhar Karim; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Leukemia is blood cancer that begins in the bone marrow and characterized by abnormal production of white blood cells. Due to advances in treatment, there has been a dramatic increase in survival rate for patients with different types of leukemia. READ MORE