Search for dissertations about: "purity determination"

Showing result 1 - 5 of 14 swedish dissertations containing the words purity determination.

  1. 1. Drug purity determination by capillary electrophoresis : Practical and theoretical aspects on peak shape and resolution

    Author : Olle Stålberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Abstract : Capillary electrophoresis was used for separation and determination ofdrugs. Structural analogues, enantiomers and rotamers were separated usingderivatized β-cyclodextrins and γ-cyclodextrins as selectors.In order to improve these separation systems different kinds of chargedamphiphiles were introduced in the background electrolyte (BGE). READ MORE

  2. 2. Multivariate spectroscopic methods for the analysis of solutions

    Author : Kent Wiberg; Sven Jacobsson; Lars Nørgaard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; UV-Vis spectroscopy; Multivariate calibration; Lidocaine; Identity; Content; PLS; SIMCA; Non-column; Diode array UV spectroscopy; DAD; Control sample; High Capacity Analysis HCA ; Fluorescence spectroscopy; Albumin; Immunoglobulin G; HPLC-DAD; Prilocaine; Peak purity determination; PCA; PARAFAC; Partial separation; Curve resolution; Analytical chemistry; Analytisk kemi;

    Abstract : In this thesis some multivariate spectroscopic methods for the analysis of solutions are proposed. Spectroscopy and multivariate data analysis form a powerful combination for obtaining both quantitative and qualitative information and it is shown how spectroscopic techniques in combination with chemometric data evaluation can be used to obtain rapid, simple and efficient analytical methods. READ MORE

  3. 3. Adsorption Studies with Liquid Chromatography : Experimental Preparations for Thorough Determination of Adsorption Data

    Author : Lena Edström; Jonas Bergquist; Lars Hagel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid chromatography; HPLC; UHPLC; Reversed phase; Preparative chromatography; Adsorption isotherm; Injection profile; Sample pH; pH stable conditions; Peak deformation; Band distortion; Overloaded band; Chiral preparative chromatography; Analytical Chemistry; Analytisk kemi;

    Abstract : Analytical chemistry is a field with a vast variety of applications. A robust companion in the field is liquid chromatography, the method used in this thesis, which is an established workhorse and a versatile tool in many different disciplines. READ MORE

  4. 4. Extraction Properties of some Nitrogen-Containing Extractants and Determination of Nitrate Complex Formation for Lanthanides and Selected Actinides Using Solvent Extraction

    Author : Sofie Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; actinides; solvent extraction; separation; lanthanides; nitrate complex formation;

    Abstract : Partitioning and transmutation of spent nuclear fuel will reduce the amount of waste and its radiotoxicity in a long-term perspective. At the same time the energy content of the spent nuclear fuel can be used more efficiently by recycling of uranium and plutonium and by using energy from the transmutation reactor. READ MORE

  5. 5. Evaluation of modified cyclodextrins for chiral separations in gas chromatography and capillary electrophoresis

    Author : Jeanette Olsson; []
    Keywords : ;

    Abstract : ABSTRACTAn evaluation of different derivatized cyclodextrins as chiral selectors for enantiomer separations has been performed with capillary electrophoresis and gas chromatography. Using gas chromatography, resolution of the enantiomers of atropisomeric PCB congeners, o,p-DDT and o,p-DDD was attempted on columns containing a mix of chiral selectors. READ MORE