Search for dissertations about: "pyelonephritis"

Showing result 6 - 10 of 31 swedish dissertations containing the word pyelonephritis.

2. 6. Influence of host genetics on innate immunity and susceptibility to urinary tract infection

   Author : Bryndis Ragnarsdottir; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; IRF3; Innate Immunity; urinary tract infections; acute pyelonephritis; asymptomatic bacteriuria; Toll-like receptor 4; CXCR1; TLR4 adaptors; polymorphisms;

   Abstract : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. READ MORE

4. 7. Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring

   Author : Adli Khalil; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and pelvis. READ MORE

5. 8. Effect of growth and development on tissue vulnerability : a study on the perinatal rat kidney

   Author : Eva Serlachius; Karolinska Institutet; Karolinska Institutet; []
   Keywords : apoptosis; development; DNA synthesis; growth; kidney; ontogeny; PKC; proximal tubular cells; pyelonephritis; rat; sodium; sodium deficiency;

   Abstract : The infant is more vulnerable than older children and adults to pathological processes, such as metabolic disturbances and kidney infection. We have speculated that the vulnerability of the infant kidney may be related to the fact that the kidney at this time is undergoing rapid growth and development. READ MORE

6. 9. Renal cell death in urinary tract infections : role of E. coli toxins

   Author : Ming Chen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Pyelonephritis; Escherichia coli toxins; ERK; LPA; cell death; carbon monoxide; hemolysin; nitric oxide; heme oxygenase-1; dexamethasone; kidney development;

   Abstract : Febrile urinary tract infections (UTI) are common bacterial illnesses in children. Several follow up studies have shown that 10-15 % of infants with pyelonephritis will develop permanent renal damage, i.e., renal scars, which in turn may lead to chronic diseases such as hypertension and renal insufficiency. READ MORE

7. 10. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections

   Author : Björn Frendéus; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Mucosal immunology; Infection Resistance; Neutrophils; Toll-like receptors; Urinary Tract Infections; Chemokine receptors; bakteriologi; virologi; mykologi;

   Abstract : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. READ MORE