Search for dissertations about: "pyrazolopyrimidine"

Found 2 swedish dissertations containing the word pyrazolopyrimidine.

  1. 1. Purine and Pyrazolopyrimidine Derivatives: Design and Synthesis of Chemical Tools for Biological Applications

    Author : David Bliman; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; purine; pyrazolopyrimidine; caged compounds; protein kinases; protein-protein interactions; fluorescence; organic synthesis;

    Abstract : Purines can be found in a multitude of naturally occurring compounds with a range of functions. This thesis describes the design and synthesis of purines and structurally related pyrazolopyrimidine derivatives intended for biological applications. READ MORE

  2. 2. All-Photonic Control of Biorelevant Processes using Molecular Photoswitches and Caged Compounds

    Author : Jesper Nilsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dithienylethene; azobenzene; drug release; kinase inhibitor; spiropyran; caged compound; live cell; spectroscopy; o-nitrobenzyl; photoswitch;

    Abstract : The development of light-controlled molecular tools for in situ regulation of biological activity holds great promise e.g. for resolving dynamic aspects of cellular signal transduction and to overcome inherent pharmaceutic limitations such as poor drug selectivity. READ MORE