Search for dissertations about: "pyrosequencing"
Showing result 11 - 15 of 106 swedish dissertations containing the word pyrosequencing.
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11. Mitochondrial DNA in Sensitive Forensic Analysis
Abstract : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. READ MORE
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12. Nucleic Acid Based Pathogen Diagnostics
Abstract : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. READ MORE
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13. Cancer Genomics - Molecular Analysis of Epithelial Cells
Abstract : Cancer is a disease involving multiple causal andsymptomatic genetic changes, collectively reflecting theselective pressures that occur during tumor development.Epithelial cancers are by far the most common type of cancerworldwide and investigation of the alterations associated withepithelial carcinogenesis will ultimately lead to improvementsin diagnosis, prognosis, prevention and treatment of thedisease. READ MORE
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14. Microfluidic bead-based methods for DNA analysis
Abstract : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. READ MORE
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15. Transcriptome and Proteome Analysis using Signature Tags
Abstract : With the full sequence of the human genome now available, anexciting era in biomedical research has started. The sequenceprovides information about all our genes and greatly increasesthe scope to compare genetic activities in different cells, toanalyze genetic variation between individuals and betweendifferent species and, most importantly, to investigatesystematically the whole genome in a gene-by-gene manner, andthus increase our understanding of gene function. READ MORE