Search for dissertations about: "pyrroline"

Found 5 swedish dissertations containing the word pyrroline.

  2. 1. Radical Cyclization Approaches to Pyrrolidines

    Author : Magnus Beşev; Troels Skrydstrup; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Radical cyclization; diastereselectivity; pyrrolidine; pyrroline; thiazoline; aziridine; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. READ MORE

  4. 2. Palladium(II)-Catalyzed Reactions of Allenes with Lithium Bromide and Cyclization of α-Amino Allenes to Pyrrolines

    Author : Attila Horváth; Jan-Erling Bäckvall; Tobias Rein; Stockholms universitet; []
    Keywords : Palladium; allene; pyrroline; palladium II -catalysis;

    Abstract : This thesis is based on three novel palladium(II)-catalyzed reactions of allenes with lithium bromide and a bromonium ion induced cyclization of allenyl amides to pyrrolines. In Paper I a 1,2-functionalization of allenes is presented where bromide adds as a first nucleophile followed by intramolecular attack by an oxygen or nitrogen nucleophile. READ MORE

  5. 3. Development of new Catalytic Methods for the Selective Synthesis of Heterocycles

    Author : Stalin Reddy Pathi Pati; Nicklas Selander; Masaharu Nakamura; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; catalysis; indium; heterocycles; Lewis acid; multicomponent reactions; furans; alkynes; organisk kemi; Organic Chemistry;

    Abstract : In the field of organic chemistry, the development of new catalytic methods for the synthesis of complex molecules from simple precursors is a top priority. The main focus of this thesis concerns the diastereoselective synthesis of heterocyclic compounds using main group elements as Lewis acid catalysts. READ MORE

  6. 4. Making Radical Cations Live Longer

    Author : Ola Persson; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; spin trapping.; 3-hexafluoropropan-2-ol; 3; 1; thallium III -based oxidants; Radical cations; electron paramagnetic resonance; Physics; Fysik; Chemistry; Kemi;

    Abstract : The acid-catalyzed rearrangement of 1,4,5,8-tetramethylnaphthalene was used to determine the acidity of media used for EPR spectral studies of radical cations. The radical cations of methyl-substituted naphthalenes were shown to undergo dimerization reactions. READ MORE

  7. 5. The Role of Proline Catabolism in Candida albicans Pathogenesis

    Author : Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. READ MORE