Search for dissertations about: "qt"

Showing result 1 - 5 of 37 swedish dissertations containing the word qt.

  2. 1. Long QT syndrome in Sweden : founder effects and associated cardiac phenotypes

    Author : Annika Winbo; Annika Rydberg; Eric Schulze-Bahr; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT Syndrome; Jervell and Lange-Nielsen Syndrome; inherited arrhythmia; founder effects; clinical genetics; haplotype analysis; mutation age; founder mutation; clinical phenotype; life-threatening cardiac events; mutation-specific; KCNQ1 gene; modifier genes; sequence variants; risk stratification; risk factor; gender; pediatrik; Pediatrics;

    Abstract : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. READ MORE

  4. 2. Autonomic cardiac control in long QT syndrome : clinical studies of arrhythmogenic triggers

    Author : Anna Lundström; Annika Rydberg; Urban Wiklund; Håkan Eliasson; Jacob Tfelt-Hansen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT syndrome; pediatrics; exercise; Holter; water immersion; arrhythmia; clinical physiology; ECG; heart rate variability; heart rate response; cardiovascular disease; hjärt- och kärlforskning; kardiologi; Cardiology; pediatrik; Pediatrics;

    Abstract : Background: Long QT syndrome (LQTS) is an inherited cardiac disease characterized by prolonged cardiac repolarization and an increased risk for life-threatening arrhythmias. These arrhythmias are typically triggered by adrenergic stimuli, such as physical activity and intense emotions, implicating that the sympathetic part of the autonomic nervous system (ANS) is involved in arrhythmogenesis. READ MORE

  5. 3. Myocardial electromechanical function in long QT syndrome

    Author : Dafni Charisopoulou; Michael Y. Henein; Annika Rydberg; Anders Jonzon; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT syndrome; stress-echocardiography; left ventricular filling; mechanical dispersion; diastolic myocardial function; exercise; arrhythmia; electromechanical window; speckle-tracking echocardiography; myocardial relaxation sequence.; kardiologi; Cardiology; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : AIM: The aim of this thesis is to assess, in LQTS and according to genotype, the myocardial electromechanical (EM) function response to exercise, its relation to symptoms and its response to b-blocker therapy. To achieve this aim, we conducted 4 studies with the following specific objectives: i. READ MORE

  6. 4. Long QT syndrome : studies of diagnostic methods

    Author : Ulla-Britt Diamant; Steen M Jensen; Annika Rydberg; Thomas Gilljam; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kardiologi; Cardiology;

    Abstract : Background: The Long QT Syndrome (LQTS) is a hereditary heart disease with risk of malignant ventricular arrhythmia and sudden cardiac death. Despite our increased knowledge about genotype and phenotype correlation we still rely on the 12-lead ECG for assessment of the QT interval and the T-wave morphology for diagnosis and risk stratification. READ MORE

  7. 5. Repolarization studies in the long QT syndrome

    Author : Pia Dahlberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; long QT syndrome; repolarization; hysteresis; vectorcardiography; QT adaptation; ventricular repolarization;

    Abstract : ABSTRACT Background: Sudden cardiac death in the young is predominantly caused by inherited cardiac conditions. Long QT syndrome (LQTS) is one of the most common of these disorders. Since risk stratification relies largely upon the heart rate (HR) corrected QT interval (QTc), it is crucial to identify an appropriate method for QT correction. READ MORE