Search for dissertations about: "quality by design tablet"

Found 5 swedish dissertations containing the words quality by design tablet.

  2. 1. Multivariate Synergies in Pharmaceutical Roll Compaction : The quality influence of raw materials and process parameters by design of experiments

    Author : Nabil Souihi; Johan Trygg; Jukka Rantanen; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roll compaction; dry granulation; mannitol; dicalcium phosphate; design of experiments; orthogonal projections to latent structures; critical quality attributes; tablet manufacturing; quality by design; design space; near-infrared chemical imaging; texture analysis; modeling; scale up; instrumented roll; Johanson model;

    Abstract : Roll compaction is a continuous process commonly used in the pharmaceutical industry for dry granulation of moisture and heat sensitive powder blends. It is intended to increase bulk density and improve flowability. READ MORE

  4. 2. Terahertz sensing for non-destructive characterisation of pharmaceutical tablets

    Author : Anis Moradikouchi; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; sensing.; non-destructive; pharmaceutical tablets; Terahertz technology; frequency domain; dielectric characterisation; porosity measurements;

    Abstract : The pharmaceutical industry is shifting from conventional batch manufacturing to continuous manufacturing. To realise continuous manufacturing, it is crucial to assess the product quality of tablets at different stages of the production line. READ MORE

  5. 3. Enhanced mobilisation and physical rehabilitation after abdominal cancer surgery : feasibility, effects, and experiences

    Author : Patrik Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer incidence is growing worldwide and, as advances in diagnostics, treatment, and rehabilitation are made, the numbers of cancer survivors are also increasing. Therefore, there is a need to find and evaluate methods to improve the lives of cancer survivors after treatment. READ MORE

  6. 4. Ergonomic Risk Assessment and Intervention through Smart Workwear Systems

    Author : Liyun Yang; Jörgen Eklund; Mikael Forsman; Karen Søgaard; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Physical Workload; Work Postures; Energy Consumption; Oxygen Uptake; Risk Assessment; Measurement Methods; Work-Related Musculoskeletal Disorders; Work-Related Ill Health; Wearable Sensors; Wearable Systems; Feedback; Ergonomic Intervention.; Fysisk arbetsbelastning; Arbetsställningar; Energiförbrukning; Syreupptag; Riskbedömning; Mätmetoder; Arbetsrelaterade muskuloskeletala besvär; Arbetsrelaterad ohälsa; Bärbara sensorer; Bärbara system; Återkoppling; Ergonomisk intervention.; Medicinsk teknologi; Medical Technology; Physical Workload;

    Abstract : The rapid development of wearable technology has provided opportunities to ergonomics research and practice with new ways for workload measurements, data analytics, risk assessment and intervention. This thesis aims at developing and evaluating methods using wearable technologies to assess physical risk factors at work, and further to give feedback to employees to improve their work techniques. READ MORE

  7. 5. Novel and refined small-scale approaches to determine the intrinsic dissolution rate of drugs

    Author : Sara B. E. Andersson; Göran Alderborn; Göran Frenning; Peter Langguth; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dissolution; intrinsic dissolution rate; poorly water-soluble compounds; single particle dissolution; solubility; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Many drugs are administered as crystalline particles compressed into tablets and taken orally. When the tablet reaches the gastrointestinal tract, it disintegrates and the drug particles dissolve in the gastrointestinal fluid. The dissolved molecules are absorbed across the intestinal membranes into the bloodstream to reach their target sites. READ MORE