Search for dissertations about: "quantitative structure-activity relationship"
Showing result 1 - 5 of 22 swedish dissertations containing the words quantitative structure-activity relationship.
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1. Physico-chemical characteristics and quantitative structure-activity relationships of PCBs
Abstract : The polychlorinated biphenyls (PCBs) comprise a group of 209 congeners varying in the number of chlorine atoms and substitution patterns. These compounds tend to be biomagnified in foodwebs and have been shown to induce an array of effects in exposed organisms. READ MORE
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2. In silico tools in risk assessment : of industrial chemicals in general and non-dioxin-like PCBs in particular
Abstract : Industrial chemicals in European Union produced or imported in volumes above 1 tonne annually, necessitate a registration within REACH. A common problem, concerning these chemicals, is deficient information and lack of data for assessing the hazards posed to human health and the environment. READ MORE
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3. Relationship between chemical structure and airway sensitizing potential for organic acid anhydrides : an animal model
Abstract : Oranic acid anhydrides (OAAs) are important reactive, low-molecular-weight industrial chemicals which induce allergic rhinitis and asthma in exposed subjects. Specific IgE has been demonstrated in a large proportion of OAA-exposed workers. READ MORE
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4. Computational methods for analyzing dioxin-like compounds and identifying potential aryl hydrocarbon receptor ligands : multivariate studies based on human and rodent in vitro data
Abstract : Polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are omnipresent and persistent environmental pollutants. In particular, 29 congeners are of special concern, and these are usually referred to as dioxin-like compounds (DLCs). READ MORE
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5. Design strategies for new drugs targeting multicomponent systems : focusing on class II MHC proteins and acetylcholinesterase
Abstract : The field of medicinal chemistry is constantly evolving. Aided by advances within techniques as well as knowledge of biological systems, increasingly complex targets and drugs can be considered. READ MORE