Search for dissertations about: "quiescent cells"

Showing result 6 - 10 of 45 swedish dissertations containing the words quiescent cells.

  2. 6. Satellite cells in human skeletal muscle : molecular identification quantification and function

    Author : Mona Lindström; Lars-Eric Thornell; Hannu Kalimo; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; satellite cell markers; NCAM; Pax7; MyoD; myogenin; DLK1 FA1; c-Met; human skeletal muscle; immunohistochemistry; muscle growth; muscle hypertrophy; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; anatomi; Human Anatomy;

    Abstract : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. READ MORE

  4. 7. Chloride Channels and Brown Fat Cells

    Author : Victor Sabanov; Jan Nedergaard; Bernd Nilius; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chloride channel; BAPTA; EGTA; Ca; Animal physiology; Zoofysiologi;

    Abstract : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. READ MORE

  5. 8. Genetic analysis of cell cycle and chromatin regulation in quiescent fission yeast cells

    Author : Yasaman Zahedi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During proliferation, cells produce their genetic materials to increase the number of cells, while in the absence of nutrients or by the induction of stimulus, the proliferative phase is stopped and entry into quiescence is triggered to increase their chance of survival. Quiescence is a reversible resting phase where cells enter, in case of nutrient deprivation or damage and induced by stimuli. READ MORE

  6. 9. Understanding the heterogeneity of the hematopoietic stem cells

    Author : Ece Somuncular; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The hematopoietic system is replenished and maintained throughout life by rare hematopoietic stem cells (HSCs) that reside in the bone marrow (BM) of adult mammals. Over the last 20 years, the advancement in the field lead to the acknowledgement of the heterogeneity within the HSC compartment unraveling the presence of HSC subsets with certain mature blood lineage preferences so called lineage-biased (Li-bi) HSCs. READ MORE

  7. 10. Development of therapeutic strategies for quiescent tumor cell populations

    Author : Xiaonan Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Phenotypic screening is an effective approach to the discovery of small-molecule drugs. In this thesis, I have used cancer cells grown as 3D microtissues (multicellular spheroids) to study the effect of anticancer drugs and as drug discovery tools. READ MORE