Search for dissertations about: "quinazolinones"

Found 2 swedish dissertations containing the word quinazolinones.

  2. 1. Synthetic development towards benzodiazepine alkaloids : total synthesis of circumdatin F and C

    Author : Anette Witt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alkaloids; benzodiazepines; cyclisation; Michael reactions; quinazolinones; synthesis.;

    Abstract : Benzodiazepine alkaloids exhibit a multitude of interesting pharmacological activities. This thesis deals with the development of synthetic methods towards such alkaloids, of which the main efforts can be divided into three parts. READ MORE

  4. 2. Synthetic studies of heterocyclic natural products

    Author : Jeffrey J Mason; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Heterocycles; alkaloids; natural products; luotonin A; cephalandole A; cephalandole B; benzoxazinone; tryptanthrin; ophiuroidine; pyrroloquinazolinone; isatin; Prey demethylation; pyridinium hydrochloride; demethylation; microwave synthesis;

    Abstract : The methods that were developed for the synthesis of the heterocyclic natural products luotonin A, ophiuroidine, cephalandole B, and the indol-3-yl-benzoxazinones of cephalandole A are described in this thesis. The reoccurrence of the 4(3H)-quinazolinone structure is a common theme throughout these studies, and an overview of some quinazoline chemistry is introduced in the first chapter. READ MORE