Search for dissertations about: "r and d"

Showing result 1 - 5 of 375 swedish dissertations containing the words r and d.

  1. 1. Standardization of Islet Isolation and Transplantation Variables

    Author : Andrew S Friberg; Olle Korsgren; Daniel Brandhorst; Paul R. V. Johnson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet isolation; standardization; enzyme; gradient separation; digital imaging analysis; DIA; transplantation outcome; islet transplantation; prediction; Medical technology; Medicinsk teknik; Medical Cell Biology; Medicinsk cellbiologi; Computerized Image Processing; Datoriserad bildbehandling;

    Abstract : Currently, the transplantation of islets of Langerhans is a viable means to maintain control of blood sugar levels and reduce the risk of hypoglycemia in defined populations with brittle type I diabetes mellitus or those requiring pancreatectomy. However, the process of islet isolation is highly variable and not all isolations result in islet numbers or quality suitable for transplantation. READ MORE

  2. 2. Organic Phosphorus Compounds in Aquatic Sediments : Towards Molecular Identification with Mass Spectrometry

    Author : Heidi De Brabandere; Monica Waldebäck; Emil Rydin; Per J. R. Sjöberg; Rolf Danielsson; William T. Cooper; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; electrospray ionisation; mass spectrometry; liquid chromatography; organic phosphorus; aquatic sediment; eutrophication; sample preparation; extraction; Analytical chemistry; Analytisk kemi;

    Abstract : Phosphorus (P) regulates trophic status in most aquatic systems. However, only bioavailable P contributes to primary production. In most lakes and shallow seas, mineralisation of sediment P into its bioavailable form and its release to the water column is important for maintaining primary production. READ MORE

  3. 3. YopD translocator function in Yersinia pseudotuberculosis type III secretion

    Author : Tiago R. D. Costa; Matthew S. Francis; William D. Picking; Umeå universitet; []
    Keywords : Y. pseudotuberculosis; T3SS; translocon; YopD; coiled-coil; effector delivery; regulation; virulence; mikrobiologi; Microbiology;

    Abstract : Type III secretion systems (T3SS) are a common feature of Gram-negative bacteria, allowing them to inject anti-host effectors into the interior of infected eukaryotic cells. By this mechanism, these virulence factors help the bacteria to modulate eukaryotic cell function in its favor and subvert host innate immunity. READ MORE

  4. 4. Development of Palladium-Promoted 11C/12C-Carbonylations and Radiosynthesis of Amyloid PET Ligands

    Author : Patrik Nordeman; Gunnar Antoni; Mats Larhed; Luke R Odell; Antony D Gee; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium; Carbonylation; Positron emission tomography; PET; Carbon-11; Fluor-18; Radiochemistry; Amyloidosis; Palladium; Karbonyleringar; Positronemissionstomografi; PET; Kol-11; Fluor-18; Radiokemi; Amyloidos; Pharmaceutical Science; Farmaceutisk vetenskap; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi; Medicinal Chemistry; Läkemedelskemi;

    Abstract : In the first part of this thesis, palladium(0)-catalyzed and -mediated carbonylations are discussed. Paper I describes a new method for the safe, efficient use of a solid carbon monoxide source in the synthesis of primary and secondary benzamides. READ MORE

  5. 5. Fiber/matrix interface crack propagation in polymeric unidirectional composite

    Author : Linqi Zhuang; Anders Holmberg; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Polymera konstruktionsmaterial; Polymeric Composite Materials;

    Abstract : Fiber/matrix interface cracking plays an important role in determining the final failure of unidirectional composites. In the present study, energy release rate (ERR) for fiber/matrix interface debond growth originated from fiber break in unidirectional composite is calculated using 5-cylinders axisymmetric and 3-D FEM models with hexagonal fiber arrangement. READ MORE