Search for dissertations about: "racemate"

Showing result 6 - 10 of 14 swedish dissertations containing the word racemate.

  2. 6. Fermentation of wheat starch hydrolysate by Lactococcus lactis: Factors affecting product formation

    Author : Karin Hofvendahl; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nutrients; temperature; pH; optical isomers; maltose; wheat; starch hydrolysate; Lactococcus lactis; lactic acid; SSF; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Lactic acid exists as two optical isomers, D- and L-lactic acid. For the production of biodegradable poly-lactic acid an optically pure product is desirable, but a racemate of known and constant ratio can also be used. Lactic acid can be produced either synthetically or fermentatively. READ MORE

  4. 7. On the Stereoselective Pharmacokinetics of Eflornithine and Prediction of Drug Tissue to Plasma Concentration Ratios

    Author : Rasmus Jansson Löfmark; Göteborgs universitet; []
    Keywords : Human African trypanosomiasis; HAT; Pharmacokinetics; NONMEM; Stereoselectivity; Eflornithine; Tissue distribution;

    Abstract : Eflornithine is one of two registered drugs for the treatment of late-stage human African trypanosomiasis, a uniformly fatal neglected disease with sixty million people are at risk of being infected. Eflornithine is efficacious but the cumbersome intravenous administration leaves numerous patients untreated. READ MORE

  5. 8. Postmortem toxicology : aspects on interpretation

    Author : Per Holmgren; Jörg Mörland; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Postmortem toxicology is a matter of analytical chemistry and the consequent interpretation of the results. Thus, both parts are of great importance to come to the right conclusion or the most probable explanation of the analytical results. READ MORE

  6. 9. Targeting EGFR and VEGFR2 tyrosine kinases with positron emission tomography : evaluation of two radiotracers

    Author : Erik Samén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Receptor tyrosine kinases (RTKs) are commonly involved in the development, growth and spread of cancer. Targeted therapy with tyrosine kinase inhibitors (TKIs) has proven a successful treatment strategy against cancers in which growth is dependent on the expression of these receptors. READ MORE

  7. 10. The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9

    Author : Mike Ufer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Drug metabolism; cytochrome P450; genetic polymorphism; genotyping; CYP2C9; phenprocoumon; warfarin; acenocoumarol; oral anticoagulants;

    Abstract : Oral anticoagulants are widely used for the prevention of thromboembolic disorders. Warfarin (WA) is most commonly used world-wide, while phenprocoumon (PPC) is the first-line anticoagulant in some European countries including Germany. Each anticoagulant exists in two different enantiomeric forms and is administered orally as a racemate. READ MORE