Search for dissertations about: "radiation-induced toxicity"

Showing result 1 - 5 of 11 swedish dissertations containing the words radiation-induced toxicity.

2. 1. Modelling late toxicity in hypofractionated radiation therapy

   Author : Niclas Pettersson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypofractionation; normal tissue complication probability; modelling; linear-quadratic model; fractionation sensitivity; late toxicity; radiation-induced rib fracture; genitourinary toxicity; stereotactic body radiation therapy; high-dose-rate brachytherapy; multimodality radiation therapy; patient-reported outcomes; prostate cancer; nsclc;

   Abstract : In hypofractionated radiation therapy (RT), the treatment is delivered by few fractions with high doses per fraction. This is in contrast to conventionally fractionated RT where the total dose is delivered in many fractions with low doses per fraction. READ MORE

4. 2. Relative biological effectiveness in proton therapy: accounting for variability and uncertainties

   Author : Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Radhe Mohan; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; relative biological effectiveness; linear energy transfer; proton track-end optimisation; radiation-induced toxicity; Medical Radiation Physics; medicinsk strålningsfysik;

   Abstract : Radiation therapy is widely used for treatments of malignant diseases. The search for the optimal radiation treatment approach for a specific case is a complex task, ultimately seeking to maximise the tumour control probability (TCP) while minimising the normal tissue complication probability (NTCP). READ MORE

5. 3. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

   Author : Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; Medical Radiation Physics; medicinsk strålningsfysik;

   Abstract : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. READ MORE

6. 4. Stereotactic body radiation therapy of primary lung cancer and metastases

   Author : Karin Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Stereotactic body radiation therapy (SBRT) has been assessed by both retrospective and prospective studies showing excellent treatment outcome with acceptable toxicity and high grade of local control. However, late presenting effects as well as further evaluating toxic effects in relation to dose-volume parameters at high-fraction doses and clinical characteristics is of the utmost importance in order to further develop the clinical application of this method. READ MORE

7. 5. Stereotactic body radiation therapy of lung tumours : clinical and dosimetric aspects

   Author : Kristin Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The general aim of this thesis was to increase the knowledge regarding some clinical and methodological aspects, relevant in view of toxicity as well as tumour control, in stereotactic body radiation therapy (SBRT) of lung tumours. In the first two studies, reirradiation and radiation-induced atelectasis were studied. READ MORE