Search for dissertations about: "radiobiological modelling"

Showing result 1 - 5 of 7 swedish dissertations containing the words radiobiological modelling.

  1. 1. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation A modelling study

    University dissertation from Stockholm : Department of Physics, Stockholm University

    Author : Emely Lindblom; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

  2. 2. Time, dose and fractionation: accounting for hypoxia in the search for optimal radiotherapy treatment parameters

    University dissertation from Stockholm : Department of Physics, Stockholm University

    Author : Emely Kjellsson Lindblom; Stockholms universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; radiobiological modelling; radiotherapy; functional imaging; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

  3. 3. Predicting Normal Tissue Complications after External Beam Radiation Therapy

    University dissertation from Stockholm : Department of Physics, Stockholm University

    Author : Caroline Olsson; Göteborgs universitet.; Gothenburg University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

    Abstract : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. READ MORE

  4. 4. Methods for image-based dosimetry and radiobiological modelling in radionuclide therapy

    University dissertation from Lund University, Faculty of Science, Department of Medical Radiation Physics

    Author : Johan Gustafsson; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide therapy; dosimetry; biologically effective dose; 177Lu-DOTATATE;

    Abstract : Strålbehandling är en av de vanligaste metoderna för att behandla cancer. I den mest använda formen av strålbehandling används en strålkälla utanför kroppen, så kallad extern strålterapi. Ett alternativ är att ge behandlingen med hjälp av ett läkemedel till vilket man har kopplat ett radioaktivt ämne, så kallad radionuklidterapi. READ MORE

  5. 5. Contouring variability in radiosurgery - dosimetric and radiobiological implications

    University dissertation from Stockholm : Department of Physics, Stockholm University

    Author : Helena Sandström; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : The use of Stereotactic Radiation Therapy (SRT) employing one large fraction of radiation, as in stereotactic radiosurgery (SRS), or few fractions of high doses, has continuously increased due to the technical development and the progress in dose delivery complemented by the positive clinical experience. The success of stereotactic radiation therapy depends on many clinical, dosimetric and radiobiological factors. READ MORE