Search for dissertations about: "radiobiological modelling"

Showing result 1 - 5 of 9 swedish dissertations containing the words radiobiological modelling.

  2. 1. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation : A modelling study

    Author : Emely Lindblom; Iuliana Toma-Dasu; Ingmar Lax; Ludvig Paul Muren; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

  4. 2. Antenna Design, Radiobiological Modelling, and Non-invasive Monitoring for Microwave Hyperthermia

    Author : Morteza Ghaderi Aram; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; UWB Antennas; Bio-Electromagnetics; Hyperthermia; Microwave Thermometry; Radiobiological Modeling;

    Abstract : The death toll of cancers is on the rise worldwide and surviving patients suffer significant side effects from conventional therapies. To reduce the level of toxicity in patients treated with the conventional treatment modalities, hyperthermia (HT) has been investigated as an adjuvant modality and shown to be a potent tumor cell sensitizer for radio- and chemotherapy. READ MORE

  5. 3. Time, dose and fractionation: accounting for hypoxia in the search for optimal radiotherapy treatment parameters

    Author : Emely Kjellsson Lindblom; Iuliana Toma-Dasu; Peter Wersäll; David J Carlson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; radiobiological modelling; radiotherapy; functional imaging; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

  6. 4. Predicting Normal Tissue Complications after External Beam Radiation Therapy

    Author : Caroline Olsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

    Abstract : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. READ MORE

  7. 5. Methods for image-based dosimetry and radiobiological modelling in radionuclide therapy

    Author : Johan Gustafsson; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide therapy; dosimetry; biologically effective dose; 177Lu-DOTATATE;

    Abstract : In radionuclide therapy (RNT), radioactive pharmaceuticals are administered for therapeutic purposes. Dosimetry, i.e. the estimation of the absorbed dose to various targets, can potentially lead to a better understanding of the therapeutic effects in RNT and allow for individualization of the therapy. READ MORE