Search for dissertations about: "radioimmunoassay"

Showing result 11 - 15 of 80 swedish dissertations containing the word radioimmunoassay.

  2. 11. Adolescent behavior : Links to early-life stress and alcohol in male and female rats

    Author : Stina Lundberg; Erika Roman; Ingrid Nylander; Heidi MB Lesscher; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; alcohol exposure; behavior; corticosterone; dynorphin; early life; endogenous opioid peptides; Met-enkephalin-Arg6Phe7 MEAP ; individual differences; multivariate concentric square field MCSF ; phenotyping; radioimmunoassay; selective breeding for alcohol consumption; voluntary alcohol intake; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Adolescence is an important developmental phase with large changes in behavior, physiology and neurobiology, which transform an individual from immature child to independent adult. Due to these changes, adolescence is a sensitive period for exposure to environmental factors such as stress and drug exposure; it is also a common age of onset for alcohol consumption as well as several psychiatric disorders. READ MORE

  4. 12. The Impact of Nandrolone Decanoate on Neuropeptidergic Mechanisms Related to Cognition, Aggression, Reward and Dependence

    Author : Kristina Magnusson; Fred Nyberg; Mathias Hallberg; Santi Mario Spampinato; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anabolic androgenic steroids; Nandrolone decanoate; Substance P; Dynorphin A; KOP receptor; Prodynorphin; Radioimmunoassay; Autoradiography; Morris water maze; PCR; Central nervous system; Biological research on drug dependence; Biologisk beroendeforskning; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : The abuse of anabolic androgenic steroids (AAS) is becoming increasingly common and may result in a range of physiological as well as psychological effects such as altered behavior in terms of increased aggression, cognitive dysfunction and addictive behavior. AAS comprise testosterone and its derivatives, of which nandrolone is one of the more common. READ MORE

  5. 13. Early Environment, Adolescent Alcohol Drinking and Neurobiological Responses to Drugs

    Author : Sara Palm; Ingrid Nylander; Anne-Lie Svensson; Lundblad Martin; Giancarlo Colombo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; beta-endorphin; dopamine; dynorphin; endogenous opioids; enkephalin; high-speed chronoamperometry; housing conditions; maternal separation; multivariate concentric square field™ test; open field test; radioimmunoassay; voluntary alcohol intake; Wistar rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Genes and environment interact to determine an individual’s vulnerability or resilience to several psychiatric disorders, including alcohol use disorder (AUD). Alcohol use is often initiated during adolescence and early onset drinking is associated with increased risk for later AUD. READ MORE

  6. 14. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma

    Author : Johan Permert; Linköpings universitet; []
    Keywords : endocrine pancreatic function; euglycemic hyperinsulinemic clamp; exocrine pancreatic adenocarcinoma; glucose metabolism; glyccogen synthesis; hyperglycemic clamp; immunohistochemistry; insulin resistance; insulin secretion; in situ hybridization; islet amuyloid polypeptide IAPP ; radioimmunoassay; subtotal pancreatectomy; MEDICINE; MEDICIN;

    Abstract : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. READ MORE

  7. 15. Artificial receptors: New opportunities for the exploitation of molecularly imprinted polymers

    Author : Lei Ye; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radioimmunoassay; Microsphere; Molecular imprinting; Drug determination; Cross-linking polymerisation; Combinatorial library; Chromatography; Chiral separation; Affinity adsorbent; Biosensor; Receptor; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik;

    Abstract : Molecular imprinting, method for creating artificial receptors that are mimics of biological antibodies and receptors, is based on the concept of creating substrate-specific recognition sites in polymeric matrices by means of template polymerisation. The polymeric receptors produced display favourable binding characteristics, such as high affinity and specificity towards the substrate molecules. READ MORE