Search for dissertations about: "radiological destruction"

Showing result 1 - 5 of 10 swedish dissertations containing the words radiological destruction.

  2. 1. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study

    Author : Ewa Berglin; Solbritt Rantapää-Dahlqvist; Thomas Skogh; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Abstract : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. READ MORE

  4. 2. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression

    Author : Antonia Boman; Solbritt Rantapää-Dahlqvist; Ewa Berglin; Gerd-Marie Alenius; Mikael Brink; Heidi Kokkonen; Inger Gjertsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Early rheumatoid arthritis; biomarker; ACPA; RANKL; disease activity; radiological destruction; cardiovascular events; hormonal factors; reumatologi; rheumatology;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. READ MORE

  5. 3. On inflammation and cardiovascular disease in patients with rheumatoid arthritis

    Author : Solveig Wållberg Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; mortality; cardiovascular disease; ischemic heart disease; inflammation; lipids; Lp a ; haemostasis; fibrinolysis; atherogenesis; thrombogenesis;

    Abstract : Patients with rheumatoid arthritis (RA) have a shorter life span than the general population. An increased death due to cardiovascular disease (CVD) has been reported. RA is characterized by synovitis and joint destruction accompanied by an acute phase reaction and systemic features. READ MORE

  6. 4. Anti-Collagen Type II Autoantibodies in an Acute Phenotype of Early Rheumatoid Arthritis

    Author : Mohammed Mullazehi; Johan Rönnelid; Bosse Nilsson; Kutty Selva Nandakumar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease with systemic inflammatory features that primarily affects small peripheral joints. Type II collagen (CII), is the most abundant collagen type in joint cartilage. Antibodies against CII (anti-CII) are found in a subpopulation of RA patients. READ MORE

  7. 5. Presence of immunological markers preceding the onset of rheumatoid arthritis

    Author : Mikael Brink; Solbritt Rantapää Dahlqvist; Anca Irinel Catrina; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; rheumatoid arthritis; anti citrullinated protein antibodies; pre-symptomatic individual; immunologi; Immunology; reumatologi; rheumatology;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. READ MORE