Search for dissertations about: "radiotracers"
Showing result 1 - 5 of 28 swedish dissertations containing the word radiotracers.
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1. Diabetes in 3D : β-cell mass assessments in disease models & evaluation of SPECT based imaging
Abstract : Diabetes is a rapidly growing disease with 415 million affected adults worldwide. The pancreatic endocrine cells, most importantly the insulin producing β-cells, play an important role in regulating blood glucose homeostasis. READ MORE
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2. Theranostic Targeting of GRPR and PSMA in Prostate Cancer
Abstract : This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples. READ MORE
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3. Pharmacological properties of radiotracers that measure p-glycoprotein function and density
Abstract : Energy-dependent transporters of the ATP-binding cassette (ABC) family regulate the movement of molecules across cellular membranes. Several of these transporters are expressed in the endothelial cells of brain microvessels (blood-brain barrier) to protect brain tissue from exposure to toxins in the blood. READ MORE
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4. Synthesis of 11C and 18F labelled radiotracers for applications in steroid-related biological systems
Abstract : .... READ MORE
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5. Targeting EGFR and VEGFR2 tyrosine kinases with positron emission tomography : evaluation of two radiotracers
Abstract : Receptor tyrosine kinases (RTKs) are commonly involved in the development, growth and spread of cancer. Targeted therapy with tyrosine kinase inhibitors (TKIs) has proven a successful treatment strategy against cancers in which growth is dependent on the expression of these receptors. READ MORE