Search for dissertations about: "rapid antibiotic susceptibility testing"

Showing result 1 - 5 of 11 swedish dissertations containing the words rapid antibiotic susceptibility testing.

2. 1. Development of a robust and rapid microfluidics-based antibiotic susceptibility test : From prototype to clinical implementation

   Author : Christer Malmberg; Johan Kreuger; Thomas Tängdén; Till Bachmann; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lab-on-a-chip; rapid antibiotic susceptibility testing; AST; sepsis; microfluidics; blood culture; Medical Cell Biology; Medicinsk cellbiologi;

   Abstract : Even though bacteria normally are rapidly cleared from the blood by the immune system, a blood stream infection may arise, in turn possibly leading to sepsis and septic shock. Sepsis is a life-threatening condition, where the inflammatory response to infection targets tissues and organs. READ MORE

4. 2. Lessons from diagnosis-prescribing and antibiotic resistance surveillance in Ujjain, India : the lull before the storm

   Author : Ashish Pathak; Karolinska Institutet; Karolinska Institutet; []
   Keywords : antibiotic prescribing;

   Abstract : Background: The evolution of antibiotic resistance is a global public health crisis building over decades. In this build-up antibiotic use has been the main driver for antibiotic resistance. READ MORE

5. 3. Silicon Nanowire Based Sensors for Bacterial Tests

   Author : Yingtao Yu; Zhen Zhang; Mihai Adrian Ionescu; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; silicon nanowire; field-effect transistor; antibiotic susceptibility test; bacterial metabolism; nanoelectromechanical sensor; multiplexed detection;

   Abstract : Rapid and reliable antibiotic susceptibility testing (AST) is urgently required to diagnose bacterial infectious diseases and avoid antibiotic misuse, providing valuable information on the efficacy of antibiotic agents and their dosages for treatment. However, the currently employed phenotypic ASTs normally demand the growth of bacteria into colonies, which usually takes more than two days. READ MORE

6. 4. Molecular characterisation of antibiotic resistance in Mycobacterium tuberculosis

   Author : Pontus Juréen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : To counteract the emergence of multi-drug resistant tuberculosis (MDR-TB) a number of approaches have been proposed, amongst which are the sound usage of the present anti-TB drugs and the development of prompt and specific tools for the diagnosis of resistance. To examine the role of drugs in the treatment of resistant TB, we investigated the general crossresistance between kanamycin and amikacin, which has been reported in numerous studies. READ MORE

7. 5. Rapid microbiological diagnosis of infections in sterile body fluids including blood

   Author : Osman Altun; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Infections of normally sterile body fluids (SBF) including blood, cerebrospinal-, pleural-, peritoneal-, pericardial and synovial fluid are critical and require early diagnosis and rapid initiation of appropriate antimicrobial therapy. With the advanced and invasive care of modern medicine, infections of SBF are increasing worldwide. READ MORE