Search for dissertations about: "reactivator"

Found 2 swedish dissertations containing the word reactivator.

  1. 1. Design strategies for new drugs targeting multicomponent systems focusing on class II MHC proteins and acetylcholinesterase

    University dissertation from Umeå : Umeå universitet

    Author : Cecilia Lindgren; Umeå universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; acetylcholinesterase; class II MHC protein; drug design; molecular dynamics simulation; multicomponent system; nerve agent; oxime; quantitative structure-activity relationship; reactivator; rheumatoid arthritis; statistical molecular design; T-cell receptor;

    Abstract : The field of medicinal chemistry is constantly evolving. Aided by advances within techniques as well as knowledge of biological systems, increasingly complex targets and drugs can be considered. READ MORE

  2. 2. Identification and validation of therapeutic targets in sarcoma models

    University dissertation from Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Author : Wessen Maruwge; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In spite of the low incidence of sarcomas, they are highly aggressive tumors, with high metastatic potential, and resistance to both chemotherapy and radiotherapy, leaving surgery as the only treatment option. There is evidently an urgent need in identifying molecular targets and oncogenic pathways in sarcomas that can be used for the development and evaluation of drugs directed against these tumors. READ MORE