Search for dissertations about: "receptor modeling"
Showing result 1 - 5 of 75 swedish dissertations containing the words receptor modeling.
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1. Source-Receptor Modeling of Air Pollution : Assessment of Source Contributions: Source Characterization and Chemometric Applications
Abstract : Particles released to the atmosphere from anthropogenic sources affect the Earth’s climate as well as the health of the population. Anthropogenic sources of atmospheric particles are e.g. the combustion of biomass and fossil fuels, road, brake and tire wear and various industrial activities. READ MORE
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2. Sources of dioxins and other POPs to the marine environment : Identification and apportionment using pattern analysis and receptor modeling
Abstract : In the studies underlying this thesis, various source tracing techniques were applied to environmental samples from the Baltic region. Comprehensive sampling and analysis of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in surface sediments in Swedish coastal and offshore areas resulted in a unique data set for this region. READ MORE
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3. Computational Modeling of the AT2 Receptor and AT2 Receptor Ligands : Investigating Ligand Binding, Structure–Activity Relationships, and Receptor-Bound Models
Abstract : Rational conversion of biologically active peptides to nonpeptide compounds with retained activity is an appealing approach in drug development. One important objective of the work presented in this thesis was to use computational modeling to aid in such a conversion of the peptide angiotensin II (Ang II, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe). READ MORE
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4. Free energy calculations of G protein-coupled receptor modulation : New methods and applications
Abstract : G protein-coupled receptors (GPCRs) are membrane proteins that transduce the signals of extracellular ligands, such as hormones, neurotransmitters and metabolites, through an intracellular response via G proteins. They are abundant in human physiology and approximately 34% of the marketed drugs target a GPCR. READ MORE
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5. Studies of the Neuropeptide Y Receptor Y2 in Human and Zebrafish
Abstract : The G-protein coupled receptors (GPCRs) comprise the largest family of receptors in humans and other vertebrates. They are embedded in the cell membrane and are activated by many different signaling molecules. Activation modulates cellular signal transduction pathways and influences many physiological processes. READ MORE