Search for dissertations about: "receptor trafficking"
Showing result 1 - 5 of 74 swedish dissertations containing the words receptor trafficking.
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1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
Abstract : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. READ MORE
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2. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation
Abstract : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. READ MORE
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3. Signalling and trafficking of the cysteinyl leukotriene receptors in intestinal epithelial cells
Abstract : Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. READ MORE
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4. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics
Abstract : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. READ MORE
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5. Adenosine receptor/dopamine receptor interactions : molecular and biochemical aspects
Abstract : The dopamine receptors have been shown to be involved in a variety of higher brain functions, such as motor control, cognition and affective states. Agonist and antagonists of dopamine receptors are widely used to treat disorders such as Parkinson's disease and schizophrenia, respectively. READ MORE