Search for dissertations about: "receptor"

Showing result 1 - 5 of 3613 swedish dissertations containing the word receptor.

  1. 1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    University dissertation from Experimentel medicinsk vetenskap, Lunds Universitet

    Author : Caroline Sandén; Lunds universitet.; Lund University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Abstract : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. READ MORE

  2. 2. Galanin receptor : studies with site-directed mutagenesis, agonists and antagonists

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Kalev Kask; Stockholms universitet.; [1995]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  3. 3. Evolution of Vertebrate Endocrine and Neuronal Gene Families Focus on Pituitary and Retina

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Daniel Ocampo Daza; Uppsala universitet.; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phylogenetics; evolution; molecular evolution; gene family evolution; genome duplication; gene duplication; oxytocin receptor; vasopressin receptor; visual opsin; transducin; growth hormone; prolactin; somatolactin; growth hormone receptor; prolactin receptor; somatostatin receptor; SSTR; IGFBP; evolution; molekylär evolution; fylogeni;

    Abstract : The duplication of genes followed by selection is perhaps the most prominent way in which molecular biological systems gain multiplicity, diversity and functional complexity in evolution. Whole genome duplications (WGDs) therefore have the potential of generating an extraordinary amount of evolutionary innovation. READ MORE

  4. 4. Galanin receptor ligands

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Johan Runesson; Stockholms universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; neurokemi med molekylär neurobiologi; Neurochemistry and Molecular Neurobiology;

    Abstract : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. READ MORE

  5. 5. Neurosteroids Induce Allosteric Effects on the NMDA Receptor Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tobias Johansson; Uppsala universitet.; [2008]
    Keywords : Pharmaceutical pharmacology; Pharmacology; neurosteroids; NMDA receptor; NR2B subunit; ifenprodil; sigma receptor; anabolic androgenic steroids; allosteric modulation; non-genomic; Farmaceutisk farmakologi;

    Abstract : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. READ MORE