Search for dissertations about: "recombinant adenoviral vector"

Found 2 swedish dissertations containing the words recombinant adenoviral vector.

  2. 1. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer

    Author : Helena Dzojic; Magnus Essand; Thomas H Tötterman; Aristides Eliopoulos; Uppsala universitet; []
    Keywords : Medicine; immunotherapy; gene therapy; prostate cancer; bladder cancer; adenoviral vector; CD40 ligand; promoter; PPT; TSTA; depsipeptide FK228; TRAMP-C2; Medicin;

    Abstract : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. READ MORE

  4. 2. Construction of Adenovirus Vectors for Studies of Protein Function and RNA Interference

    Author : Saideh Berenjian; Göran Akusjärvi; Mikael Berg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Adenovirus; viral vectors; VA RNAI II; RNAi; Tet-ON OFF; RNA splicing; Mikrobiologi; Microbiology; Mikrobiologi;

    Abstract : During an adenovirus infection the accumulation of alternatively spliced mRNAs is subjected to a tight temporal regulation. The IIIa protein is a structural protein expressed exclusively late after infection. READ MORE