Search for dissertations about: "reconstitution"

Showing result 21 - 25 of 109 swedish dissertations containing the word reconstitution.

  2. 21. From risk indices to reconstitution of immunity : studies of outcome-related factors in patients undergoing allogeneic hematopoietic stem cell transplantation

    Author : Johan Karlsson Törlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Allogeneic hematopoietic stem cell transplantation (HSCT) is a potent immunotherapeutic procedure which has the possibility to cure otherwise lethal hematological diseases. Its usability in clinical practice is limited by tangible risks of detrimental transplantation-related complications. READ MORE

  4. 22. lnduction Therapies in Multiple Sclerosis - Clinical and immunological follow-up

    Author : Sofia Sandgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple Sclerosis; Neurodegeneration; Alemtuzumab; Autologous hematopoietic stem cell transplantation; Induction therapies Immune reconstitution therapies;

    Abstract : Multiple sclerosis (MS) is a chronic disease that damages the central nervous system. Its pathophysiology is complex, and consists of inflammation and degeneration from the disease onset. The treatment of MS has continuously been developed with improved efficacy. READ MORE

  5. 23. Probing Proton Translocation in Influenza A/M2 Proteoliposomes - A systematic Approach to Membrane-Protein Reconstitutions

    Author : Thom Leiding; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : An improved method for reconstituting membrane proteins into artificial liposomes for quantitative functional analysis is presented. A number of key parameters for reconstitution by detergent removal are assessed in this thesis: The lipid-to-protein ratio, the detergent-to-lipid ratio and the lipid and cholesterol composition. READ MORE

  6. 24. Expression and role of the cytokine tyrosine kinase receptor flt3 in early hematopoiesis

    Author : Jörgen Adolfsson; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; flt3; cytokine; Hematopoiesis; stem cells;

    Abstract : Mature blood cells are crucial for life, but they have a short lifetime and thus have to be replaced. These mature blood cells are produced by lineage restricted progenitors, which themselves are generated by rare multipotent hematopoietic stem cells (HSCs) in a highly dynamic process called hematopoiesis. READ MORE

  7. 25. Mechanistic studies on the repression of cellular reaction to hypoxia as cause for chronic complications in diabetes

    Author : Sofie Eliasson Angelstig; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes Mellitus is an ongoing epidemic, causing individual suffering as well as constituting an enormous burden to society and healthcare systems globally. Much of diabetes-associated morbidity and mortality are caused by chronic diabetes complications, for which there today is no specific treatment due to an incomplete understanding of the underlying disease mechanisms. READ MORE