Search for dissertations about: "redox signaling"
Showing result 11 - 15 of 50 swedish dissertations containing the words redox signaling.
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11. Studies on Redox-proteins and Cytokines in inflammation and Cancer
Abstract : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. READ MORE
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12. Protein tyrosine phosphatases : taking a 'redoxionist' look at PDGFR signaling
Abstract : Protein Tyrosine Phosphatases (PTPs) are oxidized and inactivated by reactive oxygen species (ROS) upon stimulation of a wide range of cell surface receptors, including the platelet-derived growth factor (PDGF) receptor (PDGF R). Signaling via this receptor tyrosine kinase stimulates cell proliferation and migration, and it is associated with cancer and cardiovascular diseases. READ MORE
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13. Redox alterations in inflammatory diseases : diabetes, kidney failure and cancer
Abstract : In order to combat oxidative stress and maintain the intracellular redox homeostasis, cells are equipped with antioxidant systems. The thioredoxin and glutaredoxin systems are the major thiol reducing systems and central antioxidant systems in mammalian cells. READ MORE
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14. UVA/B induced redox alterations and apoptosis in human melanocytes
Abstract : Malignant melanoma is one of the most rapidly increasing cancers and accounts for about three-quarter of all skin cancer deaths worldwide. Despite compelling evidence that ultraviolet (UV) irradiation causes melanoma the knowledge how various wavelength spectra affect the balance between proliferation and apoptosis controlling the homeostasis of the melanocyte population is still limited. READ MORE
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15. Regulation of nitrogen fixation in Rhodospirillum rubrum : Through proteomics and beyond
Abstract : Adaptability is one of the reasons for the success of bacteria, allowing them to survive in conditions where no other organisms would be able to thrive. Nitrogen deficiency, for example, can be a limiting factor for the growth of micro-organisms, as this element is an essential part of almost all types of biomolecules. READ MORE