Search for dissertations about: "reference gene"

Showing result 1 - 5 of 163 swedish dissertations containing the words reference gene.

  1. 1. Contributions to Statistical Analysis of Gene Expression Data

    Author : Anders Sjögren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; DNA microarray;

    Abstract : .... READ MORE

  2. 2. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells

    Author : Maria Carlström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : shear stress; intraluminal pressure; endothelium; gene expression; DNA microarray; real-time RT-PCR; reference genes; smooth muscle cells; P2 receptors; TNF-alpha; urokinase-type plasminogen activator;

    Abstract : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. READ MORE

  3. 3. Making Doable Problems within Controversial Science : U.S. and Swedish Scientists’ Experience of Gene Transfer Research

    Author : Hannah Grankvist; Boel Berner; Claes-Fredrik Helgesson; Margareta Hallberg; Linköpings universitet; []
    Keywords : Gene transfer; biomedicine; controversy; situatedness; doability; doable problems; alignment; articulation work; boundary-work; frame of reference; U.S.A.; Sweden; interviews; Genterapi; biomedicin; kontrovers; doability; utförbara problem; alignment; situatedness; articulation work; gränsarbete; referensram; USA; Sverige; intervjuer.; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP;

    Abstract : This thesis explores how scientists within the controversial scientific field of gene  transfer make their research doable. Based on in-depth interviews with gene transfer scientists and key individuals from different regulatory agencies and advisory boards in Sweden and the U.S.A. READ MORE

  4. 4. Studies on the level of substance P and calcitonin gene-related peptide in cerebrospinal fluid of pregnant women and patients with chronic pain and in rat brain after spinal cord injury : Special reference to analytical aspects of neuropeptides

    Author : Zhurong Liu; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Substance P; Calcitonin gene-related peptide; Radioimmunoassay; High performance liquid chromatography; Cerebrospinal fluid and chronic pain; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Abstract : Substance P (SP) and calcitonin gene-related peptide (CGRP) are sensory peptides known to be involved innociception and inflammatory processes. It is well demonstrated that the two peptides can be released from spinal cord neurons during inflammation and chronic pain induced by peripheral nerve injury. READ MORE

  5. 5. Pharmacogenetic Studies of Antihypertensive Treatment : With Special Reference to the Renin-Angiotensin-Aldosterone System

    Author : Lisa Kurland; Heribert Schunkert; Uppsala universitet; []
    Keywords : Medical sciences; pharmacogenetics; hypertension; renin-angiotension-aldosterone system; gene polymorphisms; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Hypertension is common and constitutes an increased risk of morbidity and mortality of cardiovascular disease. Antihypertensive treatment will reduce this risk; the individual patient's response to treatment, however, is difficult to predict. READ MORE