Search for dissertations about: "regulatory focus"

Showing result 21 - 25 of 247 swedish dissertations containing the words regulatory focus.

  2. 21. Novel mechanisms in depression: focus on telomere biology and epigenetic regulation

    Author : Yabin Wei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Telomere length;

    Abstract : Depression is a complex disorder with an average lifetime prevalence from 11.1% to 14.6%. It causes serious disability and is a significant public health problem worldwide. READ MORE

  4. 22. The immortalization process of T cells : with focus on the regulation of telomere length and telomerase activity

    Author : Sofie Degerman; Göran Roos; John Sedivy; Umeå universitet; []
    Keywords : immortalization; senescence; T cells; Nijmegen breakage syndrome; telomere; telomerase; hTERT; generic aberrations; methylation; MEDICINE; MEDICIN; Pathology; patologi;

    Abstract : Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit the growth potential of most cells. READ MORE

  5. 23. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages

    Author : Judit Svensson-Arvelund; Jan Ernerudh; Maria Jenmalm; Göran Berg; Siamon Gordon; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). READ MORE

  6. 24. Toxicity of brominated flame retardants with focus on retinoid system disturbances

    Author : Sabina Litens Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Brominated flame retardants (BFR) are detected in the environment and biota all over the world. They contribute to the human body burden of industrial chemicals and exposure is mainly via food. Indoor dust contributes substantially in some exposure situations, which involve small children. READ MORE

  7. 25. Hypothalamic regulation of food intake : focus on the anx/anx mouse

    Author : Ida Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main goal of this thesis is to increase the knowledge about one of the most important tasks of the brain, the hypothalamic regulation of food intake. The hypothalamus is considered to be the brain s main center for regulation of food intake and it is integrating signals regaring energy status, from the body, to initiate a proper behavioral response. READ MORE