Search for dissertations about: "regulatory motifs"

Showing result 1 - 5 of 53 swedish dissertations containing the words regulatory motifs.

  2. 1. On diverse biophysical aspects of genetics : from the action of regulators to the characterization of transcripts

    Author : Aymeric Fouquier D´Hérouel; Erik Aurell; Felix Ritort; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription regulation; regulatory motifs; binding affinity; genetic interactions; secondary structure; sequence repeats; transcript characterization; Biological physics; Biologisk fysik;

    Abstract : Genetics is among the most rewarding fields of biology for the theoretically inclined, offering both room and need for modeling approaches in the light of an abundance of experimental data of different kinds. Many aspects of the field are today understood in terms of physical and chemical models, joined by information theoretical descriptions. READ MORE

  4. 2. Computational Modelling of Gene Regulation in Cancer : Coding the noncoding genome

    Author : Husen Muhammad Umer; Jan Komorowski; Claes Wadelius; Jan Korbel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Regulatory elements; gene regulation; cancer; motif; integrative database; software solutions for cancer data; Bioinformatics; Bioinformatik;

    Abstract : Technological advancements have enabled quantification of processes within and around us. The information stored within our body converts into petabytes of data. Processing and learning from such data requires comprehensive computational programs and software systems. READ MORE

  5. 3. Elucidation of complex diseases by machine learning

    Author : Karolina Smolinska Garbulowska; Jan Komorowski; Claes Wadelius; Tuuli Lappalainen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; machine learning; complex disease; multi-omics; regulatory element; gene regulation; transcription factor motif; networks; rough sets; Bioinformatics; Bioinformatik;

    Abstract : Uncovering the interpretability of models for complex health-related problems is a crucial task that is often neglected in machine learning (ML). The amount of available data makes the problem even more complicated. READ MORE

  6. 4. Multiple regulatory inputs for hierarchical control of phenol catabolism by Pseudomonas putida

    Author : W. K. Anjana Madhushani; Victoria Shingler; Livia Leoni; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. putida; Phenol catabolism; dmpR; dmp-System; 5’-LR; Carbon Catabolite Repression; Transcriptional Translational regulation; Crc; CrcZ; CrcY; Hfq;

    Abstract : Metabolically versatile bacteria have evolved diverse strategies to adapt to different environmental niches and respond to fluctuating physico-chemical parameters. In order to survive in soil and water habitats, they employ specific and global regulatory circuits to integrate external and internal signals to counteract stress and optimise their energy status. READ MORE

  7. 5. Control of Pistil Development in Arabidopsis thaliana by a Novel Class of Regulatory Genes

    Author : Sandra Kuusk; Eva Sundberg; John Bowman; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Biology; Biologi; fysiologisk botanik; Physiological Botany;

    Abstract : The pistil, or the gynoecium, is the female reproductive organ of the angiosperm flower and its ontogeny has been studied in the model plant Arabidopsis thaliana. The mature Arabidopsis gynoecium consists of a basal ovary that contains the ovules, a short style and an apical stigma that serves as the site of pollen adherence and germination. READ MORE