Search for dissertations about: "relapsing-remitting ms"

Showing result 1 - 5 of 33 swedish dissertations containing the words relapsing-remitting ms.

2. 1. Cognitive function and neurophysiological correlates in relapsing-remitting multiple sclerosis

   Author : Mathias Sundgren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Impaired cognitive function is a frequent consequence of multiple sclerosis (MS). It negatively affects vocational status, treatment adherence, physical independence, competence in activities of daily life, rehabilitation potential, driving safety and quality of life. READ MORE

4. 2. Biomarkers and Disease Activity in Multiple Sclerosis : A cohort study on patients with clinically isolated syndrome and relapsing remitting multiple sclerosis

   Author : Irene Håkansson; Jan Ernerudh; Charlotte Dahle; Magnus Vrethem; Jan Lycke; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : This thesis focuses on disease activity in clinically isolated syndrome (CIS) and newly diagnosed relapsing remitting multiple sclerosis (RRMS). The papers are based on data from 41 patients in a prospective longitudinal cohort study. All patients were untreated at baseline. READ MORE

5. 3. Studies of the Biology of Intrathecal Treatment in Progressive MS

   Author : Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

   Abstract : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. READ MORE

6. 4. Establishment and applications of a multiple sclerosis biobank : analysis of biomarkers and therapeutic complications in MS

   Author : Ellen Iacobaeus; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Biomarkers for disease activity and prognosis in multiple sclerosis (MS) are lacking. We established a MS biobank consisting of paired cerebrospinal fluid samples (CSF) and peripheral blood samples from MS patients and controls. READ MORE

7. 5. Curing Multiple Sclerosis : How to do it and how to prove it

   Author : Joachim Burman; Jan Fagius; Angelica Loskog; Sara Mangsbo; Paulo Muraro; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; cerebrospinal fluid; cytokines; hematopoietic stem cell transplantation; immunology; magnetic resonance imaging; multiple sclerosis; neuroimmunology; neurology; Neurology; Neurologi;

   Abstract : Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for multiple sclerosis (MS) with now more than 600 documented cases in the medical literature. Long-term remission can be achieved with this therapy, but when is it justified to claim that a patient is cured from MS? In attempt to answer this question, the outcome of the Swedish patients is described, mechanisms behind the therapeutic effect are discussed and new tools for demonstration of absence of disease have been developed. READ MORE