Search for dissertations about: "related to pathway degradation"

Showing result 1 - 5 of 62 swedish dissertations containing the words related to pathway degradation.

  2. 1. Degradation Pathways of Dimethylmercury in Natural Waters

    Author : Johannes West; Sofi Jonsson; Andrew Graham; Elena Gorokhova; Bridget Bergquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mercury; Marine; Degradation; Methylmercury; Aquatic; Environmental Sciences; miljövetenskap;

    Abstract : Mercury (Hg) is a naturally occurring toxic trace metal whose release into the environment has been (and still is) exacerbated by human activities. The bioavailability of Hg is tied to its chemical speciation, with monomethylmercury (MMHg) being the primary form of Hg that bioaccumulates and biomagnifies. READ MORE

  4. 2. Anaerobic degradation of phenol and related aromatics

    Author : Anna Karlsson; James M. Tiedje; Linköpings universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Aromatic compunds; anaerobic degradation; Fysik; Kemi; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

    Abstract : Phenol and other simple aromatic compounds have been found in water leached from landfills, showing that these types of compounds could be either present in disposed waste, or released from it via transformation and degradation processes. Hence, the fate anddegradation potential of such compounds under landfilling conditions is of great concern. READ MORE

  5. 3. The Path to Destruction : Understanding the mechanism and regulation of proteasomal degradation

    Author : Anne Beskow; Patrick Young; Ylva Engström; Bernat Crosas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteasome; ubiquitin; p97; Cnc-C; transcription factors; Nrf1; Nrf2; Molecular Biology; molekylärbiologi;

    Abstract : A majority of intracellular proteins are degraded by the ubiquitin proteasome system (UPS). In this thesis, both the mechanism of the degradation and the regulation of UPS have been investigated. The importance of the p97 ATPase for proteasomal degradation of cytosolic substrates was examined. READ MORE

  6. 4. Novel Regulators of the TGF-β Signaling Pathway

    Author : Marcin Kowanetz; Aristidis Moustakas; Carl-Henrik Heldin; Caroline Hill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-β; Smad; Id; EMT; cell cycle; SNF1LK; ubiquitin; degradation; signal transduction; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The transforming growth factor-β (TGF-β) superfamily consists of related multifunctional cytokines, which include TGF-βs, activins, and bone morphogenetic proteins (BMPs) and coordinate several biological responses in diverse cell types. The biological activity of TGF-β members is executed by transmembrane serine/threonine kinase receptors and intracellular Smad proteins. READ MORE

  7. 5. Integration and topology of membrane proteins related to diseases

    Author : Patricia Lara Vasquez; IngMarie Nilsson; Ismael Mingarro; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Membranes are boundaries that separate the cell from the external environment.   Membrane proteins can function as e.g. receptors and channels, allowing cells to communicate with the exterior and molecules to pass through the membrane. READ MORE