Search for dissertations about: "relative biological effectiveness RBE"

Showing result 1 - 5 of 20 swedish dissertations containing the words relative biological effectiveness RBE.

  2. 1. Radiobiological investigations of proton and light ion therapy

    Author : Nina Tilly; Michael Scholz; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Radiobiology; Monte Carlo method; Radiotherapy; high-energy instrumentation; Protons; Light ions; RBE; LET; Radiobiological models; Radiobiologi; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : During the last decade, the interest in proton and light ion beam therapy has increased considerably and several new centres are planned around the world. These particles have a large advantage due to their sharp physical dose distributions as compared to conventional radiotherapy beams. READ MORE

  4. 2. Radiation-induced apoptosis in human lymphocytes : studies on expression, function and effects of different radiation qualities

    Author : Annelie Meijer; Fabrizio Palitti; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Apoptosis; clonogenic survival; growth factors; chromosomal aberrations CA ; low dose-rate LDR ; linear energy transfer LET ; relative biological effectiveness RBE ; radio sensitivity; ataxia telangiectasia A-T ; Physical Biology; fysikalisk biologi;

    Abstract : We are constantly exposed to radiation. Radiation causes damage to our cells. By the removal of damaged and unwanted cells, apoptosis is considered to be one of the most indispensable defence processes for a multi-cellular organism. READ MORE

  5. 3. Relative biological effectiveness in proton therapy: accounting for variability and uncertainties

    Author : Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Radhe Mohan; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; relative biological effectiveness; linear energy transfer; proton track-end optimisation; radiation-induced toxicity; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Radiation therapy is widely used for treatments of malignant diseases. The search for the optimal radiation treatment approach for a specific case is a complex task, ultimately seeking to maximise the tumour control probability (TCP) while minimising the normal tissue complication probability (NTCP). READ MORE

  6. 4. Averaged linear energy transfer and other beam quality descriptors inr elation to relative biological effectiveness

    Author : Fredrik Kalholm; Niels Bassler; Iuliana Toma-Dasu; Emanuele Scifoni; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; LET; RBE; LQ-model; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : In radiotherapy with protons, a constant relative biological effectiveness (RBE) of 1.1 is traditionally applied, i.e. protons are assumed to be 10\% more effective than photons in killing cells. READ MORE

  7. 5. Biological effects of high energy radiation and ultra high dose rates

    Author : Björn Zackrisson; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; 50 MV x-rays; 50 MeV electrons; in vitro; in vivo; RBE; OER; ultra high dose-rate; radiobiological models; model selection; models of stochastic processes;

    Abstract : Recently a powerful electron accelerator, 50 MeV race-track microtron, has been taken into clinical use. This gives the opportunity to treat patients with higher x-ray and electron energies than before. Furthermore, treatments can be performed were the entire fractional dose can be delivered in parts of a second. READ MORE