Search for dissertations about: "release of K"

Showing result 1 - 5 of 168 swedish dissertations containing the words release of K.

  1. 1. Round window membrane and delivery of biologically active agents into the cochlea

    University dissertation from Universitetsservice US-AB

    Author : Amanj K. Saber; Karolinska Institutet.; Karolinska Institutet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery; Oto-rhino-laryngologi; Oto-Rhino-Laryngology; Biology; Biologi; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery;

    Abstract : Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue. READ MORE

  2. 2. Studies of sulfatide expression in relation to beta cell function

    University dissertation from Göteborg

    Author : Maria K. Blomqvist; Göteborgs universitet.; Gothenburg University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sulfatide; glycosphingolipid; insulin; beta cell; diabetes mellitus; animal models; beta cell line;

    Abstract : Previous studies have shown that the glycosphingolipid sulfatide (3´-sulfogalactosyl-ceramide) is present and functionally involved in pancreatic beta cells. In these cells, sulfatide is synthesised as two major isoforms, C16:0 and C24:0 sulfatide, with different length of the fatty acid chain of the ceramide moiety. READ MORE

  3. 3. Neuronal mechanisms in tendon healing : Effects of mobilization and immobilization

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Author : Daniel K-I Bring; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The incidence of tendon injuries is increasing. Tendon healing and modelling are frequently protracted, often leading to pain and impaired function so called overuse syndromes. Presumably, the sensory nervous system may contribute both to promotion of repair as well as to inhibition of healing and tissue modeling. READ MORE

  4. 4. Notch in cancer and cancer metabolism : six degrees of intracellular turbulence

    University dissertation from Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Author : Sebastian K.-J. Landor; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Notch signaling is an evolutionarily conserved cell-to-cell contact-dependent signaling mechanism in multicellular organisms directing cellular fates both in early development and adult tissues. In metazoans the Notch pathway consists of multiple paralogs of receptors and ligands constituting a complex juxtacrine communications network orchestrating organismal homeostasis. READ MORE

  5. 5. Transition Metal- and Enzyme-Catalyzed Reactions of Primary Amines and Allylic Alcohols : Powerful Tools in the Preparation of Pharmaceutically Important Compounds

    University dissertation from Stockholm, Sweden : Department of Organic Chemistry, Stockholm University

    Author : Lisa K. Thalén; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dynamic kinetic resolution; racemization; catalysis; hydrogen transfer; kinetic resolution; norsertraline; alpha-methyl carboxylic acids; pipecoloxylidide; Organic Chemistry; organisk kemi;

    Abstract : Dynamic kinetic resolution (DKR) has been applied to primary amines utilizing a ruthenium catalyst and an (R)-selective lipase to provide the corresponding amides in up to 95% isolated yield and up to >99% ee. Further investigations of the chemoenzymatic DKR of amines show that it is general and can be applied to a wide range of amines. READ MORE