Search for dissertations about: "reoxygenation"

Showing result 1 - 5 of 15 swedish dissertations containing the word reoxygenation.

2. 1. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation : A modelling study

   Author : Emely Lindblom; Iuliana Toma-Dasu; Ingmar Lax; Ludvig Paul Muren; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; Medical Radiation Physics; medicinsk strålningsfysik;

   Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

4. 2. Baltic Sea sediments : Source and sink for metal contamination

   Author : Sina Shahabi-Ghahfarokhi; João Marcelo Ketzer; Alessandro Amorosi; Linnéuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Baltic Sea; sediments; acid sulfate soil; metal; remediation; reoxygenation; X-ray absorption spectroscopy; Environmental Chemistry; Miljökemi; Miljövetenskap; Environmental Science;

   Abstract : The Baltic Sea sediments record spatial and temporal information about metalsand metalloids (hereafter referred to as metals), which could help to understandthe past and present contamination sinks in different basins. In addition, giventhe expanding anoxic zones in the Baltic Sea, the response of metals to artificialreoxygenation is poorly understood. READ MORE

5. 3. Hypoxia-induced phenotypic modulation of human neuroblastoma cells

   Author : Linda Holmquist Mengelbier; Institutionen för translationell medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; reoxygenation; HIF-2a; HIF-1a; differentiation; hypoxia; neuroblastoma;

   Abstract : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. READ MORE

6. 4. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

   Author : Faranak Azarbayjani; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

   Abstract : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. READ MORE

7. 5. Studies on Cell Injury Induced by Hypoxia-Reoxygenation and Oxidized Low Density Lipoprotein : With Special Reference to the Protectiove Effect of Mixed Tocopherols, Omega-3 Fatty Acids and Transforming Growth Factor-beta1

   Author : Hongjiang Chen; Tom Saldeen; Christer Sylven; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Tocopherols; fish oil; TGF-β1; NOS; adhesion molecules; MMPs; PKB; MAPK; H-R; Ox-LDL; Myocytes; HCAECs; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Hypoxia-reoxygenation (H-R) injury is an important clinical phenomenon in patients with coronary artery disease (CAD). Endothelial injury is a critical step in the initiation and progression of atherosclerosis. Therefore, endothelial and cardiomyocyte protection has been considered an effective step in prevention and treatment of CAD. READ MORE