Search for dissertations about: "reperfusion damage"

Showing result 1 - 5 of 48 swedish dissertations containing the words reperfusion damage.

  1. 1. Cellular and molecular mechanisms of ischemic brain damage in hyperglycemic rats

    University dissertation from Experimental Brain Research, Lund University

    Author : Hiroyuki Uchino; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Reperfusion injury; Mitochondria; Permeability transition; Cyclosporin A; Neurotrophins; Seizures; Brain damage; Acidosis; Hypercapnia; Ischemia; Hyperglycemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : The present study is centered on mechanisms of ischemic brain damage in hyperglycemic animals, and in those in which exaggerated intraischemic acidosis was induced by superimposed hypercapnia in normoglycemic animals. The initial experiments were focussed on the pathophysiology of postischemic seizures. READ MORE

  2. 2. Hepatic ischemia-reperfusion injury

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Author : Melroy Alistair D'Souza; Karolinska Institutet.; Karolinska Institutet.; [2020]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. READ MORE

  3. 3. Myocardial ischemia and reperfusion injury, clinical and experimental studies

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Author : Karin Åström-Olsson; Göteborgs universitet.; Gothenburg University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardium; ischemia; reperfusion injury; FKBP12; FKBP12.6;

    Abstract : Acute myocardial infarction is the consequence of an occluded nutrient coronary artery. Reperfusion reduces infarct size and enhances the rate of survival. But reperfusion may also, in itself, cause reversible injury, stunning and arrhythmias, as well as irreversible lethal reperfusion injury. READ MORE

  4. 4. Experimental cardiopulmonary cerebral resuscitation with special reference to cerebral eicosanoid production and free radical scavengers

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Xiaoli Liu; Marianne Forsman; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; cerebral resuscitation; reperfusion damage; oxidative injury; eicosanoid; free radical scavenger; neurological function; alkaline buffer; S-PBN; PBN; Anestesiologi och intensivvård; MEDICINE Surgery Anaesthetics and intensive care; MEDICIN Kirurgi Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

    Abstract : Reperfusion injury after restoration of spontaneous circulation (ROSC) is often considered one of the predominant factors in determining neurological outcome in cardiac arrest. Therefore one of the main targets of experimental and clinical studies has been to mitigate this reperfusion injury. READ MORE

  5. 5. Influence of Oxidative Stress on Muscle and Bone

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Bengt Östman; Karl Michaëlsson; Lars Nordsletten; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; coenzyme Q10; exercise; ischaemia; isprostanes; muscle; oxidative stress; oxygen radicals; reperfusion; tocopherol; MEDICINE Surgery Surgical research Orthopaedics; MEDICIN Kirurgi Kirurgisk forskning Ortopedi; Orthopaedics; ortopedi;

    Abstract : Reactive oxygen species (ROS) induce oxidative stress and although are primarily recognized for playing a deleterious biological role, they can be beneficial to cell systems. ROS are extremely short-lived and normally tightly regulated by antioxidant defence systems. READ MORE