Search for dissertations about: "reperfusion damage"

Showing result 11 - 15 of 51 swedish dissertations containing the words reperfusion damage.

2. 11. Mechanisms of Brain Damage Following Focal Cerebral Ischemia: Changes in Ion Homeostasis and the Importance of Free Radical Formation

   Author : Gunilla Gidö; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PBN; free radicals; potassium; extracellular calcium; neuronal damage; energy-depletion; hypoglycemia; Cerebral focal ischemia; spreading depression; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Abstract : In this thesis mechanisms of neuronal damage were investigated in an experimental stroke model i.e focal ischemia. The influence of SD-induced calcium transients on neuronal damage were studied in animals with reduced energy supply. READ MORE

4. 12. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

   Author : Faranak Azarbayjani; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

   Abstract : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. READ MORE

5. 13. Experimental studies on Damage Control Surgery and Intraabdominal Hypertension

   Author : Pia Olofsson; Thore Wikström; Kenth Johansson; Sten Lennquist; Fikri M Abu-Zidan; Louis Riddez; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Damage control surgery (DCS) offers an alternative to the traditional surgical management of complex or multiple injuries in critically injured patients. If a patient survives the initial phase of DCS, complications may occur, one of these being intraabdominal hypertension (IAH) and it´s potential development into the abdominal compartment syndrome. READ MORE

6. 14. Cerebral Protection in Experimental Cardiopulmonary Resuscitation : With Special Reference to the Effects of Methylene Blue

   Author : Adriana Miclescu; Lars Wiklund; Samar Basu; Jo Kramer-Johansen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; cardiopulmonary resuscitation; reperfusion injury; methylene blue; nitric oxide; nitric oxide synthases; blood-brain barrier; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

   Abstract : Although survival rates are increasing, brain injury continues to be a leading cause of death after cardiac arrest (CA). Permanent brain damage after CA is determined by limited tolerance to ischemia from CA and cardiopulmonary resuscitation (CPR), as well as the unique cerebral response to reperfusion after return of spontaneous circulation (ROSC). READ MORE

7. 15. Redox processes and oxidative stress in cell and tissue damage

   Author : Lisa Arodin Selenius; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Oxidative stress is described as an imbalance between oxidants and antioxidants, with a shift towards the oxidants. When the antioxidative systems are insufficient or the production of radicals is increased oxidative damage can occur, damaging DNA, lipids, and proteins. Oxidative stress has been implicated in several pathologies. READ MORE