Search for dissertations about: "reperfusion damage"

Showing result 21 - 25 of 51 swedish dissertations containing the words reperfusion damage.

  2. 21. Ischemic and Hypoglycemic Brain Damage, Involvement of the Mitochondrial Permeability Transition Pore

    Author : Hans Friberg; Lund Wallenberg Neurocentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondrial permeability transition pore; mitochondria; apoptosis; neuronal death; brain; ischemia; hypoglycemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Brain damage from ischemia-reperfusion and hypoglycemia are major causes of morbidity and mortality. Therapeutic strategies include hypothermia, glutamate-receptor blockade, immunosuppression and lately treatment aiming at preserving mitochondrial integrity and function. READ MORE

  4. 22. Coagulation Inhibition and Development of Myocardial Damage in ST-Elevation Myocardial Infarction

    Author : Gunnar Frostfeldt; Marianne Hartford; Uppsala universitet; []
    Keywords : Medical sciences; myocardial infarction; fibrinolysis; lmw-heparin; coagulation; troponin-T; PET; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : In 101 patients with ST-elevation myocardial infarction treated with streptokinase the additional effects of lmw-heparin (dalteparin) were investigated. The prognostic value of troponin-T (TnT) was elucidated and the development of myocardial damage was investigated with Positron Emission Tomography (PET). READ MORE

  5. 23. Myocardial ischemia-reperfusion and cardioprotection. A study with microdialysis in a porcine model

    Author : Carsten Metzsch; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heart preservation; metoprolol; levosimendan; beta-blockers; pharmacological preconditioning; myocardial ischemia; cardioprotection; glycerol; microdialysis; cold cardioplegic storage;

    Abstract : The studies in this thesis are based on questions raised in the clinical setting. Perioperative myocardial ischemia occurs more often than recognized. This may lead to myocardial infarction, increased morbidity, mortality, and health care costs. READ MORE

  6. 24. Oxidative stress in cell and tissue damage and selenium-based therapeutics in cancer

    Author : Rim Jawad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Redox homeostasis is the balance between cellular prooxidants and antioxidants, maintained by the interplay of electrons. Reactive oxygen species (ROS) is a term for molecules with unpaired valence electrons or unstable bonds. READ MORE

  7. 25. Monitoring and prevention of ischaemia-reperfusion injury in liver transplantation : experimental and clinical studies

    Author : Grzegorz Nowak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver function after transplantation is determined not only by the quality of the donor organ or recipient related factors, but also by factors associated with organ preservation. During preservation, the liver graft is exposed to ischaemia and reperfusion with subsequent injury to the transplanted liver. READ MORE