Search for dissertations about: "reperfusion injury"

Showing result 1 - 5 of 89 swedish dissertations containing the words reperfusion injury.

  1. 1. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

    Author : Anna Börjesson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

    Abstract : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. READ MORE

  2. 2. Hepatic ischemia-reperfusion injury

    Author : Melroy Alistair D'Souza; Karolinska Institutet; Karolinska Institutet; []

    Abstract : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. READ MORE

  3. 3. Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat

    Author : Jan Melin; Bengt Rippe; Uppsala universitet; []
    Keywords : Medical sciences; diabetes mellitus; ischemia reperfusion; rat; end-stage renal disease; inflammation; fibrosis; hyaluronan; CD44; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. READ MORE

  4. 4. Myocardial ischemia and reperfusion injury, clinical and experimental studies

    Author : Karin Åström-Olsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : myocardium; ischemia; reperfusion injury; FKBP12; FKBP12.6;

    Abstract : Acute myocardial infarction is the consequence of an occluded nutrient coronary artery. Reperfusion reduces infarct size and enhances the rate of survival. But reperfusion may also, in itself, cause reversible injury, stunning and arrhythmias, as well as irreversible lethal reperfusion injury. READ MORE

  5. 5. Pharmacological interventions against myocardial ischemia and reperfusion injury

    Author : Lars O Karlsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Myocardial reperfusion injury; opioids; cyclosporine A;

    Abstract : Background: Ischaemic heart disease is the leading cause of death in the industrialised world. Although the concept of early restoration of coronary blood-flow constitutes an important factor to reduce the injury caused by myocardial ischaemia, reperfusion in itself can aggravate the damage to myocardial tissue, a phenomenon denoted myocardial reperfusion injury. READ MORE